300706-96-1

Basic information

• Product Name: (E)-3-Bromo-4-phenylbut-3-en-2-ol
• Synonyms: (E)-3-Bromo-4-phenylbut-3-en-2-ol
• CAS NO: 300706-96-1
• Molecular Weight: 227.101
• Mol File: 300706-96-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (E)-3-Bromo-4-phenylbut-3-en-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-3-Bromo-4-phenylbut-3-en-2-ol(300706-96-1)
• EPA Substance Registry System: (E)-3-Bromo-4-phenylbut-3-en-2-ol(300706-96-1)

Safety Data

• Hazardous Substances Data: 300706-96-1(Hazardous Substances Data)

Upstream product

• 937-53-1 (Z)-4-phenylbut-3-en-2-one 
• 32147-21-0 (3E)-3-bromo-4-phenyl-3-buten-2-one 
• 1896-62-4 (E)-benzalacetone 
• 6310-44-7 3,4-dibromo-4-phenylbutan-2-one 

Downstream Products

• 32644-22-7 1-methyl-3-phenylallene 
• 405933-21-3 (E)-3-bromo-4-phenylbut-3-en-2-yl 2,2,2-trichloroacetate 
• 300707-04-4 N-((E)-2-Bromo-1-methyl-3-phenyl-allyl)-N-(2-nitro-phenyl)-methanesulfonamide 
• 300707-12-4 N-(2-Aminophenyl)-N-[(E)-2-bromo-1-methyl-3-phenylprop-2-enyl]methanesulfonamide 

Relevant articles and documents

Synthesis of allenes from allylic alcohol derivatives bearing a bromine atom using a palladium(0)/diethylzinc system

A general and efficient synthesis of allenes using a palladium(0)/diethylzinc system is described. Treatment of mesylates or trichloroacetates of (E)- or (Z)-2-bromoalk-2-en-1-ols with diethylzinc in the presence of a catalytic amount of palladium(0) affords allenes bearing an aminoalkyl, alkyl, or aryl substituent(s) in good to high yields. No transfer of chirality from the stereogenic center carrying the mesyloxy group to the allene was observed.

A new synthesis of indoles

Aryl radical cyclisation onto appropriate vinyl bromides leads to a new route to indoles.