32147-21-0Relevant articles and documents
The α-arylation of α-bromo- and α-chloroenones using palladium-catalysed cross-coupling
Banks, James C.,Mele, David Van,Frost, Christopher G.
, p. 2863 - 2866 (2007/10/03)
The palladium-catalysed cross-coupling reaction of various arylboronic acids with α-bromoenones and α-chloroenones offers an operationally simple approach to the synthesis of both cyclic and acyclic α-arylenones.
A convenient halogenation of α,β-unsaturated carbonyl compounds with OXONE and hydrohalic acid (HBr,HCl)
Kim, Kyoung-Mahn,Park, In-Hwan
, p. 2641 - 2644 (2007/10/03)
Mixtures of OXONE and hydrobromic acid or hydrochloric acid afford solutions of bromine or chlorine, respectively, α-Bromo- or α-chloro-α,β-unsaturated carbonyl compounds were prepared by addition of hydrobromic acid or hydrochloric acid to the mixture of
Synthesis of allenes from allylic alcohol derivatives bearing a bromine atom using a palladium(0)/diethylzinc system
Ohno, Hiroaki,Miyamura, Kumiko,Tanaka, Tetsuaki,Oishi, Shinya,Toda, Ayako,Takemoto, Yoshiji,Fujii, Nobutaka,Ibuka, Toshiro
, p. 1359 - 1367 (2007/10/03)
A general and efficient synthesis of allenes using a palladium(0)/diethylzinc system is described. Treatment of mesylates or trichloroacetates of (E)- or (Z)-2-bromoalk-2-en-1-ols with diethylzinc in the presence of a catalytic amount of palladium(0) affords allenes bearing an aminoalkyl, alkyl, or aryl substituent(s) in good to high yields. No transfer of chirality from the stereogenic center carrying the mesyloxy group to the allene was observed.
A convenient and useful method of preparation of α-bromo enones from the corresponding enones using organic ammonium tribromide (OATB)
Bose, Gopal,Bujar Barua, Pankaj M.,Chaudhuri, Mihir K.,Kalita, Dipak,Khan, Abu T.
, p. 290 - 291 (2007/10/03)
Various acyclic α-bromo enones 2 as well as cyclic α-bromo enones 4 can be prepared from the corresponding acyclic enones 1 and cyclic enones 3 respectively, in a one-pot procedure by employing organic ammonium tribromide, such as cetyltrimethylammonium t
A radical based addition-elimination route for the preparation of indoles
Murphy, John A.,Scott, Karen A.,Sinclair, Rhoha S.,Martin, Concepcion Gonzalez,Kennedy, Alan R.,Lewis, Norman
, p. 2395 - 2408 (2007/10/03)
Indoles, including tricyclic derivatives, are produced by cyclisations of aryl radicals onto vinyl halides followed by elimination of halide radical and tautomerism of the resulting product; the aryl radicals are produced using "clean methodology" either by reaction of iodide ions with arenediazonium salts or by reaction of phosphorus-centred radicals with aryl iodides. The Royal Society of Chemistry 2000.
A new synthesis of indoles
Murphy, John A.,Scott, Karen A.,Sinclair, Rhona S.,Lewis, Norman
, p. 7295 - 7298 (2007/10/03)
Aryl radical cyclisation onto appropriate vinyl bromides leads to a new route to indoles.
α-Keto Dianion Precursors via Conjugate Additions to Cyclic α-Bromo Enones
Kowalski, Conrad J.,Weber, Ann E.,Fields, Kevin W.
, p. 5088 - 5093 (2007/10/02)
Successful conjugate to 2-bromocyclohexenone and 2-bromocyclopentenone have been achieved with a variety of lithium homocuprates, mixed cyanocuprates, and lithium tri-sec-butylborohydride as well.In all cases the resulting α-bromo enolate anions could be
