300809-91-0Relevant articles and documents
Conformationally constrained analogues of diacylglycerol (DAG). 17. Contrast between sn-1 and sn-2 DAG lactones in binding to protein kinase C
Tamamura,Bienfait,Nacro,Lewin,Blumberg,Marquez
, p. 3209 - 3217 (2007/10/03)
In previous work, we have obtained potent protein kinase C (PK-C) ligands with low-namomolar binding affinities by constructing diacylglycerol (DAG) mimetics in which the sn-2 carbonyl of DAG was constrained into a lactone ring. An additional structural e