184873-70-9

Basic information

• Product Name: (5S)-5-[(1S)-2-benzyloxy-1-hydroxyethyl]tetrahydrofuran-2-one
• Synonyms: (5S)-5-[(1S)-2-benzyloxy-1-hydroxyethyl]tetrahydrofuran-2-one
• CAS NO: 184873-70-9
• Molecular Weight: 236.268
• Mol File: 184873-70-9.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: (5S)-5-[(1S)-2-benzyloxy-1-hydroxyethyl]tetrahydrofuran-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (5S)-5-[(1S)-2-benzyloxy-1-hydroxyethyl]tetrahydrofuran-2-one(184873-70-9)
• EPA Substance Registry System: (5S)-5-[(1S)-2-benzyloxy-1-hydroxyethyl]tetrahydrofuran-2-one(184873-70-9)

Safety Data

• Hazardous Substances Data: 184873-70-9(Hazardous Substances Data)

Upstream product

• 692753-37-0 (E)-6-benzyloxyhex-4-enoic acid methyl ester 
• 210100-08-6 O²,O³,O⁵,O⁶-tetraacetyl-L-galactonic acid-lactone 
• 667870-34-0 (4E)-ethyl-6-benzyloxy hex-4-enoate 
• 184873-69-6 Acetic acid (S)-2-acetoxy-1-((S)-5-oxo-tetrahydro-furan-2-yl)-ethyl ester 
• 79580-62-4 tri-O-acetyl-3-deoxy-D-arabino-hexono-1,4-lactone 
• 93553-66-3 1-(benzyloxy)but-3-en-2-ol 
• 100-39-0 benzyl bromide 

Downstream Products

• 184873-71-0 Tetradecanoic acid (S)-2-benzyloxy-1-((S)-5-oxo-tetrahydro-furan-2-yl)-ethyl ester 
• 667870-35-1 Methanesulfonic acid (S)-2-benzyloxy-1-((S)-5-oxo-tetrahydro-furan-2-yl)-ethyl ester 
• 300809-77-2 (Z)-5(S)-[1(S)-(2,2-dimethyl-1,1-diphenyl-1-silapropoxy)-2-(phenylmethoxy)ethyl]-3-nonylideneoxolan-2-one 
• 300809-76-1 (E)-5(S)-[1(S)-(2,2-dimethyl-1,1-diphenyl-1-silapropoxy)-2-(phenylmethoxy)ethyl]-3-nonylideneoxolan-2-one 
• 300809-74-9 5(S)-[1(S)-(2,2-dimethyl-1,1-diphenyl-1-silapropoxy)-2-(phenylmethoxy)ethyl]-3-(hydroxynonyl)oxolan-2-one 
• 300809-88-5 (Z)-1(S)-[4-nonylidene-3-oxo-(2-oxolan-1(S)-yl)]-2-(phenylmethoxy)ethyl nonanoate 
• 300809-89-6 (E)-1(S)-[4-nonylidene-3-oxo-(2-oxolan-1(S)-yl)]-2-(phenylmethoxy)ethyl nonanoate 
• 300809-75-0 5(S)-[1(S)-(2,2-dimethyl-1,1-diphenyl-1-silapropoxy)-2-(phenylmethoxy)ethyl]-3-[hydroxy-4-methyl-3-(methylethyl)pentyl]oxolan-2-one 
• 300809-81-8 (Z)-5(S)-[1(S)-(2,2-dimethyl-1,1-diphenyl-1-silapropoxy)-2-(phenylmethoxy)ethyl]-3-[4-methyl-3-(methylethyl)pentylidene]oxolan-2-one 
• 300809-79-4 (E)-5(S)-[1(S)-(2,2-dimethyl-1,1-diphenyl-1-silapropoxy)-2-(phenylmethoxy)ethyl]-3-[4-methyl-3-(methylethyl)pentylidene]oxolan-2-one 
• 300809-92-1 (Z)-1(S)-{4-[4-methyl-(1-methylethyl)pentylidene]-3-oxo-(2-oxolan-1(S)-yl)}-2-(phenylmethoxy)ethyl nonanoate 
• 300809-93-2 (E)-1(S)-{4-[4-methyl-(1-methylethyl)pentylidene]-3-oxo-(2-oxolan-1(S)-yl)}-2-(phenylmethoxy)ethyl nonanoate 
• 300809-90-9 (Z)-1(S)-[4-nonylidene-3-oxo-(2-oxolan-1(S)-yl)]-2-(phenylmethoxy)ethyl 4-methyl-3-(1-methylethyl)pentanoate 
• 300809-91-0 (E)-1(S)-[4-nonylidene-3-oxo-(2-oxolan-1(S)-yl)]-2-(phenylmethoxy)ethyl 4-methyl-3-(1-methylethyl)pentanoate 

Relevant articles and documents

Chirality induction and chiron approaches to enantioselective total synthesis of α-lipoic acid

Abstract An efficient, short and convenient asymmetric synthesis of (R)-(+)-lipoic acid in seven steps from chiral hydroxy aldehyde with 32.5% overall yield is described. Synthesis of S and R enantiomers of α-lipoic acid from cis-1,4-butene diol derived chiral lactone is reported with 34 % overall yield. The present synthesis involves use of simple reaction conditions making it a convenient synthesis.

Stereoselective synthesis of microcarpalide

Microcarpalide is a strong microfilament disrupting agent. The convergent and stereoselective synthesis of microcarpalide was succeeded via Julia olefination and macrolactonization.

An efficient stereoselective synthesis of (2S,4S,5R)-(-)- and (2R,4R,5S)-(+)-bulgecinine

A short synthetic route to (-)-and (+)-bulgecinine, the amino acid moiety of the bulgecins was achieved from the readily available nonchiral pool starting material cis-2-butene-1,4-diol employing a Claisen orthoester rearrangement and Sharpless asymmetric