30089-62-4

Basic information

• Product Name: 1,4-DIMETHOXY-2-(1-PHENYL-ETHYL)-BENZENE
• Synonyms: 1,4-DIMETHOXY-2-(1-PHENYL-ETHYL)-BENZENE
• CAS NO: 30089-62-4
• Molecular Formula: C₁₆H₁₈O₂
• Molecular Weight: 242.31292
• Mol File: 30089-62-4.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 359.2°C at 760 mmHg
• Flash Point: 138.6°C
• Appearance: /
• Density: 1.035g/cm³
• Vapor Pressure: 5.01E-05mmHg at 25°C
• Refractive Index: 1.54
• CAS DataBase Reference: 1,4-DIMETHOXY-2-(1-PHENYL-ETHYL)-BENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-DIMETHOXY-2-(1-PHENYL-ETHYL)-BENZENE(30089-62-4)
• EPA Substance Registry System: 1,4-DIMETHOXY-2-(1-PHENYL-ETHYL)-BENZENE(30089-62-4)

Safety Data

• Hazardous Substances Data: 30089-62-4(Hazardous Substances Data)

Usage

Class

Methoxybenzene derivatives

Psychoactive Drug

Yes

Hallucinogenic Effects

Yes

Structural Similarity

Mescaline

Benzene Ring

Present

Methoxy Groups

Two

Phenethylamine Moiety

Present

Controlled Substance

Yes, in many countries

Potential for Abuse

Yes

Recreational Use

Yes, for hallucinogenic effects

Side Effects

Can have harmful and potentially serious side effects

InChI:InChI=1/C16H18O2/c1-12(13-7-5-4-6-8-13)15-11-14(17-2)9-10-16(15)18-3/h4-12H,1-3H3

Upstream product

• 98-85-1 1-Phenylethanol 
• 150-78-7 1,4-dimethoxybezene 
• 100-42-5 styrene 
• 93-92-5 1-phenylethyl acetate 

Relevant articles and documents

Graphene-Catalyzed Direct Friedel-Crafts Alkylation Reactions: Mechanism, Selectivity, and Synthetic Utility

Transition-metal-catalyzed alkylation reactions of arenes have become a central transformation in organic synthesis. Herein, we report the first general strategy for alkylation of arenes with styrenes and alcohols catalyzed by carbon-based materials, exploiting the unique property of graphenes to produce valuable diarylalkane products in high yields and excellent regioselectivity. The protocol is characterized by a wide substrate scope and excellent functional group tolerance. Notably, this process constitutes the first general application of graphenes to promote direct C-C bond formation utilizing polar functional groups anchored on the GO surface, thus opening the door for an array of functional group alkylations using benign and readily available graphene materials. Mechanistic studies suggest that the reaction proceeds via a tandem catalysis mechanism in which both of the coupling partners are activated by interaction with the GO surface.

Microwave-accelerated alkylation of arenes/heteroarenes with benzylic alcohols using antimony(III) chloride as catalyst: Synthesis of O-heterocycles

An efficient protocol for alkylation of electron-rich arenes/heteroarenes with benzylic alcohols under microwave irradiation using antimony(III) chloride as catalyst has been developed. The mild reaction conditions, high yields, operational simplicity, and applicability to various substrates render the approach a useful route for the synthesis of diaryl/triarylalkane. In addition, a new route for the conversion of ortho-alkenylated phenols into functionalized O-heterocycles has been accomplished. Georg Thieme Verlag Stuttgart ? New York.

Highly efficient iodine-catalyzed hydroarylation of arenes with styrenes

Iodine mediates the hydroarylation of styrenes with arenes and heteroarenes to afford 1,1-diarylalkanes in good to high yields. Details regarding the substrate scope and selectivity of this hydroarylation reaction are discussed.