30091-13-5

Upstream product

• 434-64-0 perfluorotoluene 
• 2696-92-6 nitrosylchloride 
• 1868-85-5 (2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)hydrazine 
• 1227710-63-5 (4-methoxyphenyl)(2,3,5,6-tetrafluoro-4-trifluoromethylphenyl)iodonium toluene-4-sulfonate 

Downstream Products

• 93832-49-6 1,3,4-trifluoro-7,9-dimethyl-2-trifluoromethyl-11H-dibenzo<1,2>diazepine 
• 40474-38-2 Perfluor-(4-methylazobenzol) 
• 53887-84-6 SS-Dimethyl-N(perfluor-p-tolyl)sulfoximid 
• 53887-86-8 2-C₆H₅NH-4-CF₃-C₆F₃NNC₆H₅ 
• 53887-87-9 2,6-bis(C₆H₅NH)-4-CF₃-C₆F₃NNC₆H₅ 
• 53887-85-7 4-CF₃-C₆F₄NH-cyclo-C₆H₁₁ 

Relevant academic research and scientific papers

Convenient synthesis of pure fluorous alkyl azides at multigram scale

The reaction of F-alkylation reagents including (perfluoroalkyl)alkyl halides and sulfonates [Rfn(CH2)mX (X?=?Br, I, OTs, OTf)], and a slight excess of NaN3 in DMSO at 100?°C for 5?h, followed by steam distillat

Perfluoroaryl Azide Staudinger Reaction: A Fast and Bioorthogonal Reaction

We report a fast Staudinger reaction between perfluoroaryl azides (PFAAs) and aryl phosphines, which occurs readily under ambient conditions. A rate constant as high as 18 m?1 s?1 was obtained between methyl 4-azido-2,3,5,6-tetrafluorobenzoate and methyl 2-(diphenylphosphanyl)benzoate in CD3CN/D2O. Furthermore, the iminophosphorane product was stable toward hydrolysis and aza-phosphonium ylide reactions. This PFAA Staudinger reaction proved to be an excellent bioothorgonal reaction. PFAA-derivatized mannosamine and galactosamine were successfully transformed into cell-surface glycans and efficiently labeled with phosphine-derivatized fluorophore-conjugated bovine serum albumin.

A versatile and highly reactive polyfluorinated hypervalent iodine (III) compound

(Figure Presented) Hyper-reactive: A highly reactive, fully fluorinated hypervalent iodine reagent (see formula) mediates new transformations (e.g. the one-pot conversion of sulfides to sulfoximines) and serves as a stoichiometric oxidant in well-established reactions (e.g. C-C bond cleavage and the conversion of alcohols into aldehydes).