30095-48-8

Basic information

• Product Name: 2-bromo-1-(4-isobutylphenyl)ethanone
• Synonyms: 2-bromo-1-(4-isobutylphenyl)ethanone
• CAS NO: 30095-48-8
• Molecular Formula: C₁₂H₁₅BrO
• Molecular Weight: 255.1509
• Mol File: 30095-48-8.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-bromo-1-(4-isobutylphenyl)ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-bromo-1-(4-isobutylphenyl)ethanone(30095-48-8)
• EPA Substance Registry System: 2-bromo-1-(4-isobutylphenyl)ethanone(30095-48-8)

Safety Data

• Hazardous Substances Data: 30095-48-8(Hazardous Substances Data)

Upstream product

• 104483-03-6 2-(4-isobutyl-phenyl)-2-hydroxy-acetic acid 
• 38861-78-8 1-(4-isobutyl-phenyl)-ethanone 

Downstream Products

• 887908-68-1 benzofuran-2-yl-(4-isobutyl-phenyl)-methanone 
• 1174747-82-0 C₁₈H₂₇O₆P 
• 1430109-77-5 (E)-1,4-bis(4-isobutylphenyl)but-2-ene-1,4-dione 
• 1178572-14-9 C₂₁H₂₀N₂O 
• 887908-73-8 benzofuran-2-yl-(4-isobutyl-phenyl)-methanol 

Relevant articles and documents

Organocatalytic Enantioselective Selenosulfonylation of a C-C Double Bond to Form Two Stereogenic Centers in an Aqueous Medium

Organocatalytic selenosulfonylation of the C-C double bond of α,β-unsaturated ketones to construct two contiguous stereogenic centers in an aqueous medium was described. A series of α-selenyl and β-sulfonyl ketones with various functional groups were synthesized in good yields and enantioselectivities with saturated NaCl solution as the solvent. In addition, this protocol had been successfully scaled up to a decagram scale via a simple workup procedure.

Process for preparing α-hydroxy-acids and compounds obtained by this process

The invention relates to a process for preparing α-hydroxy-acids of general formula: STR1 in which R represents hydrogen or a lower alkyl radical and Cy represents a phenyl, naphthyl or heterocyclic radical, these latter three radicals optionally comprising one or more substituents selected from the group consisting of lower alkyl, lower alkenyl, lower alkynyl, lower alkoxy radicals and halogen atoms, process which comprises the treatment of an α-monohalogenated ketone of general formula: STR2 in which R and Cy have the same meaning as above and X represents chlorine, bromine or iodine, in the presence of an aqueous solution of an alkali metal hydroxide, a non-polar organic solvent selected from an aromatic or alicyclic hydrocarbon and oxygen in excess optionally in the presence of an inert gas, the treatment being carried out at a temperature ranging from the boiling temperature of the reaction medium at atmospheric pressure and 240° C. under pressure and the alkali metal so formed is then acidified to obtain the desired acid.