3010-09-1

Basic information

• Product Name: Propanenitrile, 2-[(phenylmethyl)amino]-
• CAS NO: 3010-09-1
• Molecular Formula: C10H12N2
• Molecular Weight: 160.219
• Mol File: 3010-09-1.mol

Chemical Properties

• CAS DataBase Reference: Propanenitrile, 2-[(phenylmethyl)amino]-(CAS DataBase Reference)
• NIST Chemistry Reference: Propanenitrile, 2-[(phenylmethyl)amino]-(3010-09-1)
• EPA Substance Registry System: Propanenitrile, 2-[(phenylmethyl)amino]-(3010-09-1)

Safety Data

• Hazardous Substances Data: 3010-09-1(Hazardous Substances Data)

Upstream product

• 151-50-8 potassium cyanide 
• 75-07-0 acetaldehyde 
• 100-46-9 benzylamine 
• 773837-37-9 sodium cyanide 
• 14321-27-8 N-ethylbenzylamine 
• 19481-82-4 2-bromopropionitrile 

Downstream Products

• 1384289-56-8 methyl 2-((benzyl(1-cyanoethyl)amino)methyl)acrylate 
• 96617-27-5 2-{Benzyl-[(1S,2S)-2-hydroxy-2-(1-phenyl-vinyl)-cyclobutyl]-amino}-propionitrile 
• 219487-85-1 C₂₀H₁₉ClN₄O₃ 
• 219487-72-6 2-Amino-N-benzyl-N-(cyano-methyl-methyl)-benzamide 
• 173200-35-6 1-benzyl-3,5-dichloro-6-methylpyrazin-2(1H)-one 
• 35118-09-3 N-Benzyl-N-(cyano-methyl-methyl)-2-nitro-benzamide 

Relevant articles and documents

Controllable access to multi-substituted imidazoles: Via palladium(II)-catalyzed C-C coupling and C-N condensation cascade reactions

A novel and efficient protocol for the synthesis of various 2,4-disubstituted, 1,2,4-trisubstituted and 1,2,4,5-tetra-substituted imidazoles via cascade palladium catalyzed C-C coupling followed by intramolecular C-N bond formation was developed. Readily accessible boronic acids and N-substituted-2-aminoacetonitriles were firstly reported as starting materials to construct di-, tri-, and tetra-substituted imidazoles in good to excellent yield.

1-Cyanoformamidines. Formation during the RuO4-mediated oxidation of secondary amines

When performed in the presence of cyanide and at pH smaller than 5, the RuO4-mediated oxidation of secondary amines Bn-NH-R (1a-b; R=Me, Et) gave mainly 1-cyanoformamidines Bn-NR-C(=NH)-CN (2a-b) and their hydrolysis products Bn-NR-COCN (3a-b), Bn-NR-CN (4a-b), Bn-NR-CONH2 (5a-b). Carboxamides 5a-b can result also directly from 1a-b. (Chemical Equation Presented).

RuO4-mediated oxidation of secondary amines. Part 1. Are hydroxylamines the main intermediates?

The RuO4-catalyzed oxidation of secondary amines Bn-NH-CH2R (1a and b; R=H, Me) gave mainly amides, but minute amounts of nitrones PhCH=N(O)-CH2R (9a and b) and traces of Bn-N(OH)-CH2R (R=H, 4a) were also detect

Design and synthesis of novel type VI-like β-turn mimetics. Diversity at the i+1 and the i+2 position

In this paper, a synthetic approach for functionalised 5-aminopiperidinone- 2-carboxylate (APC) systems as non-pro cis-peptide bond containing external β-turn mimics is presented. The scope and limitations of the synthetic method are discussed and the pot

A new entry to [1,2,4]triazolo[1,5-α][1,4]benzodiazepin-6-ones via intramolecular nitrilimine cycloaddition to the cyano group

A series of [1,2,4]triazolo[1,5-α][1,4]benzodiazepin-6-ones of potential pharmacological interest have been synthesised by means of intramolecular nitrilimine cycloadditions to the cyano group.