301152-33-0Relevant academic research and scientific papers
3-Deoxyclocinnamox: The first high-affinity, nonpeptide μ-opioid antagonist lacking a phenolic hydroxyl group
Derrick,Neilan,Andes,Husbands,Woods,Traynor,Lewis
, p. 3348 - 3350 (2000)
The C3-substituent in morphinan opioids is of critical importance; the 3-OH group is usually associated with very much higher affinity for μ-receptors than H or -OMe. However in this series of 14β-cinnamoylamino derivatives the codeinones (e.g.
