301219-24-9Relevant academic research and scientific papers
4-Heterocyclylpiperidines as selective high-affinity ligands at the human dopamine D4 receptor
Rowley, Michael,Collins, Ian,Broughton, Howard B.,Davey, William B.,Baker, Raymond,Emms, Frances,Marwood, Rosemarie,Patel, Shil,Patel, Smita,Ragan, C. Ian,Freedman, Stephen B.,Ball, Richard,Leeson, Paul D.
, p. 2374 - 2385 (2007/10/03)
5-(4-Chlorophenyl)-3-(1-(4-chlorobenzyl)piperidin-4-yl)pyrazole (3) was identified from screening of the Merck sample collection as a human dopamine D4 (hD4) receptor ligand with moderate affinity (61 nM) and 4-fold selectivity over human D2 (hD2) recepto
