301225-52-5 Usage
Chemical structure
Contains a BOC (tert-butoxycarbonyl) protecting group, a piperidine ring, and a pyridine moiety.
Application
Commonly used in organic synthesis as a building block to construct various complex molecules.
BOC protecting group
Can be removed under mild acidic conditions to reveal a free amine group.
Utility
Useful for the synthesis of peptides and other bioactive molecules due to the presence of the free amine group.
Structural motifs
Presence of pyridine and piperidine rings makes it a potential candidate for drug development.
Pharmaceutical relevance
These structural motifs are commonly found in pharmaceutical compounds.
Versatility
Serves as a chemical building block with potential applications in both academic research and industrial settings.
Check Digit Verification of cas no
The CAS Registry Mumber 301225-52-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,0,1,2,2 and 5 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 301225-52:
(8*3)+(7*0)+(6*1)+(5*2)+(4*2)+(3*5)+(2*5)+(1*2)=75
75 % 10 = 5
So 301225-52-5 is a valid CAS Registry Number.
301225-52-5Relevant articles and documents
LINEAR GLYCOSIDASE INHIBITORS
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Page/Page column 92, (2019/03/14)
Compounds of formula (I) wherein A, R, W, Q, L, n and m have the meaning according to the claims can be employed, inter alia, for the treatment of tauopathies and Alzheimer's disease.
1,3,4 Trisubstituted pyrrolidine CCR5 receptor antagonists bearing 4-aminoheterocycle substituted piperidine side chains
Willoughby, Christopher A.,Rosauer, Keith G.,Hale, Jeffery J.,Budhu, Richard J.,Mills, Sander G.,Chapman, Kevin T.,MacCoss, Malcolm,Malkowitz, Lorraine,Springer, Martin S.,Gould, Sandra L.,DeMartino, Julie A.,Siciliano, Salvatore J.,Cascieri, Margaret A.,Carella, Anthony,Carver, Gwen,Holmes, Karen,Schleif, William A.,Danzeisen, Renee,Hazuda, Daria,Kessler, Joseph,Lineberger, Janet,Miller, Michael,Emini, Emilio A.
, p. 427 - 431 (2007/10/03)
A new class of 4-(aminoheterocycle)piperidine derived 1,3,4 trisubstituted pyrrolidine CCR5 antagonists is reported. Compound 4a is shown to have good binding affinity (1.8 nM) and antiviral activity in PBMC's (IC95=50 nM). Compound 4a also has improved PK properties relative to 1.
