301311-68-2

Upstream product

• 1666-13-3 diphenyl diselenide 
• 103971-83-1 3-phenylselenyl propionaldehyde 
• 55179-51-6 (-)-aminomenthol 
• 104-55-2 3-phenyl-propenal 
• 301311-53-5 2-(2'-phenylselenoethyl)-perhydro-1,3-benzoxazine 

Downstream Products

• 301311-80-8 (1R,2S,5R)-2-[1-((S)-3-Benzyl-piperidin-1-yl)-1-methyl-ethyl]-5-methyl-cyclohexanol 
• 301311-72-8 (1S,7R,8aR,9aS,10aS)-1-Benzyl-7,10,10-trimethyl-decahydro-9-oxa-4a-aza-anthracene 

Relevant academic research and scientific papers

Regio- and stereoselective 6-exo-trig radical cyclisations onto chiral perhydro-1,3-benzoxazines: Synthesis of enantiopure 3-alkylpiperidines

Enantiopure 3-alkyl substituted piperidines are prepared by diastereoselective 6-exo-trig cyclisation of perhydro-1,3-benzoxazines derived from (-)-(8)-amino menthol. The diastereoselective cyclisation is promoted by tributyltin hydride, and the competitive 1,5-hydrogen migration depends on the position of the acceptor double bond and the radical site. Copyright (C) 2000 Elsevier Science Ltd.