30133-76-7

Upstream product

• 128457-41-0 [4-(7-Chloro-5,11-dihydro-10-thia-dibenzo[a,d]cyclohepten-5-yloxy)-benzyl]-dimethyl-amine 
• 30133-75-6 2,11-dichloro-6,11-dihydrodibenzothiepin 

Downstream Products

• 96122-37-1 1-<2-(2-chloro-6,11-dihydrodibenzothiepin-11-yloxy)ethyl>-4-(4-chloro-3-trifluoromethylphenyl)piperidin-4-ol 
• 119475-97-7 3-(2-chloro-6,11-dihydrodibenzothiepin-11-yloxy)quinuclidine 
• 96122-25-7 2-chloro-11-<2-(4-methylpiperazino)ethoxy>-6,11-dihydrodibenzothiepin 

Relevant academic research and scientific papers

POTENTIAL ANTIDEPRESSANTS. SYNTHESIS OF 6,11-DIHYDRODIBENZOTHIEPIN-11-YL (DIMETHYLAMINOMETHYL)PHENYL ETHERS, SULFIDES, AMINES AND SOME RELATED COMPOUNDS

Reactions of 11-chloro-6,11-dihydrodibenzothiepin and its 2-bromo derivative with the isomeric (dimethylaminomethyl)phenols, (dimethylaminomethyl)thiophenols, and (dimethylaminomethyl)anilines in toluene afforded the title compounds IIIb,c, Va, VIIIa,b,c, and Xa,b,c.Reactions of 11-chloro-6,11-dihydrodibenzothiepin and its 2-chloro and 2-methyl derivatives with N,N-dimethyl-2-(4-aminophenoxy)ethylamine and N,N-dimethyl-3-(4-aminophenoxy)propylamine by heating in dimethylformamide in the presence of sodium carbonate gave the diamino ethers XI-XIV.Thecompounds showed only indications of the antidepressant agents profile and some antimicrobial effects in vitro.