30148-18-6

Usage

Uses

Used in Pharmaceutical Research and Drug Development:
(4-CHLOROPHENYL)(1-METHYL-1H-IMIDAZOL-2-YL)METHANONE is used as a pharmacological agent for its potential therapeutic applications. Its unique chemical structure allows it to interact with various biological targets, making it a valuable compound in the search for new drugs and treatments.
Used in Organic Synthesis:
In the field of organic synthesis, (4-CHLOROPHENYL)(1-METHYL-1H-IMIDAZOL-2-YL)METHANONE serves as a key intermediate or building block for the synthesis of more complex molecules. Its functional groups can be further modified or reacted to create a wide range of chemical products.
Used in Medicinal Chemistry:
(4-CHLOROPHENYL)(1-METHYL-1H-IMIDAZOL-2-YL)METHANONE is also utilized in medicinal chemistry for the design and development of new drugs. Its structural features can be exploited to optimize the pharmacokinetic and pharmacodynamic properties of drug candidates, potentially leading to more effective and safer medications.

InChI:InChI=1/C11H9ClN2O/c1-14-7-6-13-11(14)10(15)8-2-4-9(12)5-3-8/h2-7H,1H3

Upstream product

• 616-47-7 1-methyl-1H-imidazole 
• 104-88-1 4-chlorobenzaldehyde 
• 1266333-81-6 3-methyl-1-[methyl(phenyl)amino]-1H-imidazol-3-ium iodide 

Downstream Products

• 122155-38-8 α-(4-chlorophenyl)-α-methyl-1-methyl-1H-imidazole-2-methanol 
• 122155-24-2 (4-chlorophenyl)(1-methyl-1H-imidazol-2-yl)methanol 

Relevant academic research and scientific papers

Facile preparation of aromatic ketones from aromatic bromides and arenes with aldehydes

Aromatic ketones were efficiently prepared in good yields by the reactions of aryl bromides with n-BuLi, followed by the reactions with aromatic aldehydes or aliphatic aldehydes and the subsequent treatment with molecular iodine and K2CO3, in a one-pot method. The same treatment of arenes, instead of aromatic bromides, also provided the corresponding aromatic ketones in good yields. Using these methods, various diaryl ketones and alkyl aryl ketones bearing electron-rich aromatics and electron-deficient aromatics could be prepared efficiently by a simple, transition-metal-free, and therefore environmentally benign experimental procedure.

Synthesis of 2-keto-imidazoles utilizing N -arylamino-substituted N-heterocyclic carbenes

A new method for the synthesis of 2-aroyl-, 2-heteroaroyl-, and 2-cinnamoyl-substituted imidazoles in very good yields has been developed. The reaction employs novel nitrogen heterocyclic carbenes (NHCs), namely, N-arylamino-substituted NHCs, formed in situ from the corresponding imidazolium salts, and subsequent reaction with aromatic, heteroaromatic, and cinnamic aldehydes without utilizing transition metals or expensive specialized catalysts.(Figure Presented)