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α-Benzoyloxyprotoporphyrin IX dimethyl ester (BPDME) is a synthetic derivative of protoporphyrin IX, a naturally occurring porphyrin compound found in hemoglobin and other biological systems. BPDME is characterized by the presence of a benzoyloxy group and two methyl ester groups attached to the protoporphyrin IX structure. This chemical modification enhances its photosensitizing properties, making it a promising candidate for photodynamic therapy (PDT) applications, particularly in the treatment of various types of cancer. BPDME exhibits strong absorption in the red region of the light spectrum, which allows for deeper tissue penetration and more effective activation of the photosensitizer upon exposure to light. The chemical's ability to generate reactive oxygen species upon light activation leads to the destruction of cancer cells, making BPDME a valuable tool in the field of oncology and medical research.

30151-72-5

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30151-72-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 30151-72-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,0,1,5 and 1 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 30151-72:
(7*3)+(6*0)+(5*1)+(4*5)+(3*1)+(2*7)+(1*2)=65
65 % 10 = 5
So 30151-72-5 is a valid CAS Registry Number.

30151-72-5Downstream Products

30151-72-5Relevant academic research and scientific papers

Synthesis of the Four meso-Oxyprotoporphyrin Isomers

Jackson, Anthony H.,Rao, K. R. Nagaraja,Wilkins, Martyn

, p. 794 - 796 (1982)

The four isomers of meso-oxyprotoporphyrin dimethyl esters have been prepared via direct oxidation of protoporphyrin IX dimethyl ester, separated by h.p.l.c., and identified by conversion into the corresponding biliverdins.

Synthetic and Biosynthetic Studies of Porphyrins.Part 11.The Synthesis of meso Oxygenated Protoporphyrins.

Jackson, Anthony H.,Rao, K. R. Nagaraja,Wilkins,Martyn

, p. 307 - 312 (2007/10/02)

Treatment of protoporphyrin IX dimethyl ester (12) with benzoyl peroxideaffords a mixyure of the four isomeric meso-benzoiloxy derivaties (13) These have been separated by h.p.l.c. and distinguished from each other by hydrolysis to the corresponding oxophlorins (oxyporphyrins),insertionof iron to form the oxyhaems (3),and oxidation by molecular oxygen to the corresponding biliverdins (7).

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