30158-46-4

Usage

Explanation

The molecular formula represents the number of atoms of each element present in a molecule of the compound.

Explanation

This describes the arrangement of atoms and functional groups in the molecule, which determines its chemical properties and reactivity.

Explanation

These are specific groups of atoms within the molecule that have distinct chemical properties and reactivity.

Explanation

The compound is used as a starting material or intermediate in the synthesis of other organic compounds, particularly in the development of new drugs and agrochemicals.

Explanation

Due to its chemical structure and reactivity, the compound should be handled with caution to minimize potential hazards.

Explanation

The presence of the nitro group makes the compound a versatile building block for the synthesis of a wide range of organic compounds.

Explanation

Most organic compounds with molecular weights above 200 g/mol are solids at room temperature, and 1-[(2-chloro-2-phenylethyl)sulfonyl]-4-nitrobenzene has a molecular weight of approximately 327 g/mol.

Explanation

The compound's structure, containing aromatic rings and a sulfonyl group, suggests it would be more soluble in organic solvents than in water.

Explanation

The compound is expected to be stable at room temperature and in the absence of strong acids, bases, or oxidizing agents.

Explanation

The compound's chemical structure suggests it may have hazardous properties, and appropriate safety measures should be taken when handling it.

Chemical structure

Nitrobenzene derivative with a sulfonyl group attached to a phenylethyl group, and a chlorine atom attached to the phenyl ring.

Functional groups

Nitro group, sulfonyl group, phenyl group, and chloro group.

Applications

Organic synthesis and pharmaceutical research.

Potential risks

May pose risks to human health and the environment.

Reactivity

Useful intermediate for the synthesis of various organic compounds.

Physical state

Likely a solid at room temperature (based on molecular weight and structure).

Solubility

Likely soluble in organic solvents such as dichloromethane, acetone, or ethanol.

Stability

Stable under normal laboratory conditions.

Hazards

Potential hazards include irritant, toxic, or corrosive properties.

Upstream product

• 100-42-5 styrene 
• 98-74-8 4-Nitrobenzenesulfonyl chloride 
• 100-01-6 4-nitro-aniline 

Relevant academic research and scientific papers

Visible-Light-Induced Chemoselective Synthesis of α-Chloro and Vinyl Sulfones by Sulfonylation of Alkenes

Direct sulfonylation between alkenes and sulfonyl chloride was achieved at room temperature by a visible-light-induced photoredox process. This method allows the chemoselective synthesis of α-chloro and vinyl sulfone derivatives with moderate to high yields. The selectivity of the reaction was fully controlled by the electronic properties of the alkenes.

Making Copper Photocatalysis Even More Robust and Economic: Photoredox Catalysis with [CuII(dmp)2Cl]Cl

The CuII complex [CuII(dmp)2Cl]Cl (dmp = 2,9-dimethyl-1,10-phenanthroline) is evaluated as an oxidation stable precursor for visible-light-mediated CuI-photoredox catalysis, being efficient and considerable more cost-effective compared to previously established copper(I) photocatalysts. Its performance and efficiency are demonstrated within a broad scope of atom transfer radical addition (ATRA) reactions, allowing the 1,2-difunctionalization of alkenes, as well as for decarboxylative coupling and an Appel reaction. Moreover, the utility of the complex is shown by various gram-scale functionalizations of styrene, thus suggesting [CuII(dmp)2Cl]Cl to be a low-priced alternative precatalyst for processes run on scale. Furthermore, this study provides UV/Vis evidence on the mechanism for the visible light activation of CuII complexes.

Visible-Light-Mediated Regioselective Chlorosulfonylation of Alkenes and Alkynes: Introducing the Cu(II) Complex [Cu(dap)Cl2] to Photochemical ATRA Reactions

A visible-light-mediated photocatalyzed protocol utilizing copper-phenanthroline-based catalysts has been developed that can convert a large number of olefins into their chlorosulfonylated products. Besides the Cu(I) complex [Cu(dap)2]Cl, now well-established in photo-ATRA processes, the corresponding Cu(II) complex [Cu(dap)Cl2] proved to be often even more efficient in the title reaction, being advantageous from an economic point of view but also opening up new avenues for photoredox catalysis. Moreover, the copper complexes outperformed commonly used ruthenium, iridium, or organic dye based photocatalysts, owing to their ability to stabilize or interact with transient radicals by inner sphere mechanisms. The use of stoichiometric Na2CO3 in combination with the copper photocatalysts was found to be essential to convert unactivated olefins to the desired products, in contrast to activated olefins for which no additive was required. As suggested by appropriate control experiments, the role of Na2CO3 is attributed to prevention of poisoning of the catalyst.

Cu-Catalyzed photoredox chlorosulfonation of alkenes and alkynes

Visible-light photoredox chlorosulfonation of alkenes and alkynes is achieved using a Cu photocatalyst. The reactions occur under mild conditions, have broad scope, and have high functional group tolerance.

Method for synthesizing alpha-chlorosulfone

The invention discloses a method for synthesizing alpha-chlorosulfone. The method comprises adding an organic solvent, sulfuryl chloride, an olefin and a catalyst Ru(bpy)3Cl2.6H2O into a glass reactorin a nitrogen atmosphere under anaerobic conditions and stirring the materials under LED lamp irradiation at the room temperature for 2-6h. The method firstly uses a blue LED lamp to promote the synthesis of alpha-chlorosulfone. The method has simple processes, is free of heating or other special equipment and has a high reaction yield.

Visible-light-promoted oxidative difunctionalization of alkenes with sulfonyl chlorides to access β-keto sulfones under aerobic conditions

A mild, practical and efficient strategy to prepare β-keto sulfones has been developed by visible light promoted reactions. This reaction involves Ir(ppy)2(dtbbpy)PF6 catalyzed direct funcationalization of alkenes with sulfonyl chlorides under mild conditions. Air was used as oxidant without any additives. The transformation affords the corresponding products in moderate to high yields.