30161-01-4Relevant academic research and scientific papers
Aromatic ring opening of fused thiophenes via organolithium addition to sulfur
Hill,De Vleeschauwer,Houde,Belley
, p. 407 - 410 (1998)
Organolithium reagents can add to the sulfur atom of thiophenes that are substituted by a chlorine atom and fused to another aromatic system, at -78°C, to give ortho-substituted aryl sulfides.
Aromatic ring-opening of 2-fluorobenzothiophenes by alkyllithiums
Belley, Michel,Douida, Zohra,Mancuso, John,De Vleeschauwer, Marc
, p. 247 - 250 (2007/10/03)
Diphenylacetylenes are obtained when alkyllithium reagents are added to 3-aryl-2-fluorobenzothiophenes at low temperature. The aromatic ring-opening mechanism involves a nucleophilic addition of the alkyllithium to the sulfur atom of the thiophene. The re
