301646-92-4Relevant academic research and scientific papers
Synthesis and microbiological activity of some novel 5-benzamido- and 5- phenylacetamido- substituted 2-phenylbenzoxazole derivatives
Sener, Esin Aki,Temiz Arpaci, Oezlem,Yalcin, Ismail,Altanlar, Nurten
, p. 397 - 405 (2007/10/03)
The synthesis and microbiological activity of a new series of 5- benzamido- and 5-phenylacetamidosubstituted-2-phenylbenzoxazole derivatives (1-26) were described. The in vitro microbiological activity of the compounds was determined against Gram-positive, Gram-negative bacteria and the yeast Candida albicans in comparison with standard drugs. Microbiological results indicated that the synthesized compounds possessed a broad spectrum of activity against the tested microorganisms. The compounds 1, 21, 25 showed higher activity than tetracycline and streptomycin against Pseudomonas aeruginosa. (C) 2000 Elsevier Science S.A.
