301666-61-5

Basic information

• Product Name: ethyl 3-(bromomethyl)picolinate
• Synonyms: ethyl 3-(bromomethyl)picolinate
• CAS NO: 301666-61-5
• Molecular Formula: C₉H₁₀BrNO₂
• Molecular Weight: 244.09
• Mol File: 301666-61-5.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: ethyl 3-(bromomethyl)picolinate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 3-(bromomethyl)picolinate(301666-61-5)
• EPA Substance Registry System: ethyl 3-(bromomethyl)picolinate(301666-61-5)

Safety Data

• Hazardous Substances Data: 301666-61-5(Hazardous Substances Data)

Upstream product

• 4021-07-2 3-methyl-pyridine-2-carboxylic acid 
• 20970-75-6 2-cyano-3-methylpyridine 
• 1003-73-2 3-picoline-N-oxide 
• 58997-10-7 ethyl 3-methylpyridine-2-carboxylate 

Downstream Products

• 301666-62-6 ethyl 3-(cyanomethyl)picolinate 
• 1211584-54-1 5,6-dihydro-pyrrolo[3,4-b]pyridin-7-one 

Relevant articles and documents

NOVEL CLOSTRIDIUM DIFFICILE TOXIN INHIBITORS

The present invention relates to benzodiazepine derivative compounds of formula (I), or pharmaceutically acceptable salts thereof. The present benzodiazepine compounds are useful Clostridium difficile inhibitors in the treatment of Clostridium difficile infection in humans. The present invention provides a pharmaceutical composition containing benzodiazepine compounds of formula (I) and a method of making as well as a method of using the same in treating patients infected with Clostridium difficile infection by administering the same. The compounds of the present invention may be used in combination with additional antibiotics or anti-toxin antibody drugs.

Preparation of some Thiopyranopyridine Derivatives

In the first systematic study of thiopyranopyridines in which the sulphur atom is separated from the pyridine ring by one carbon atom, the four isomeric enol esters, ethyl 5-hydroxy-8H-thiopyranopyridine-6-carboxylate (4b), ethyl 8-hydroxy-5H-thiopyranopyridine-7-carboxylate (5b), and ethyl 4-hydroxy-1H-thiopyrano- and pyridine-3-carboxylate (6b) and (7b), have been synthesised.Improved methods for the preparation of their pyridine precursors are described.With phenylhydrazine, the enol esters (4b) - (7b) give condensed pyrazole derivatives (15) - (18), which have dipolar structures; with hot mineral acid they undergo decarboxylative hydrolysis, to give the corresponding oxothiopyranopyridines (4a) - (7a).