301668-92-8

Basic information

• Product Name: N,N-bis(pyridin-2-ylmethyl)benzenamine
• Synonyms: N,N-bis(pyridin-2-ylmethyl)benzenamine
• CAS NO: 301668-92-8
• Molecular Weight: 275.353
• Mol File: 301668-92-8.mol
• Article Data: 23

Chemical Properties

• CAS DataBase Reference: N,N-bis(pyridin-2-ylmethyl)benzenamine(CAS DataBase Reference)
• NIST Chemistry Reference: N,N-bis(pyridin-2-ylmethyl)benzenamine(301668-92-8)
• EPA Substance Registry System: N,N-bis(pyridin-2-ylmethyl)benzenamine(301668-92-8)

Safety Data

• Hazardous Substances Data: 301668-92-8(Hazardous Substances Data)

Upstream product

• 591-50-4 iodobenzene 
• 1539-42-0 bis[(2-pyridyl)methyl]amine 
• 586-98-1 2-Hydroxymethylpyridine 
• 6959-48-4 3-chloromethylpyridinium chloride 
• 62-53-3 aniline 
• 1203669-57-1 bis-pyridin-2-ylmethyl-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-phenyl]-amine 
• 6959-47-3 2-chloromethylpyridine hydrochloride 
• 4377-33-7 2-chloromethylpyridine 

Downstream Products

• 946005-73-8 4-(N,N-di-(pyridine-2-ylmethyl)amino)benzaldehyde 
• 498534-44-4 dichlorido(N,N-bis(2-pyridylmethyl)benzeneamine)copper(II) 
• 1221742-50-2 N,N’-di-[2-pyridylmethyl]-4-nitroaniline 
• 1129527-13-4 (4-iodo-phenyl)-bis-pyridin-2-ylmethyl-amine 
• 1203669-55-9 [4-(bis-pyridin-2-ylmethyl-amino)-phenyl]-(3,4-dimethoxy-phenyl)-methanone 
• 1616255-21-0 N,N-di(2-picolyl)aniline(chloro)Pd^II perchlorate 

Relevant articles and documents

A selective triarylmethine-based spectroscopic probe for Zn2+ ion monitoring

We report the synthesis and application of a novel probe of the di-2-picolylamine (DPA)-conjugated triarylmethine (TAM) dye which has aimed at detecting Zn2+ ions. The 1:2 binding stoichiometry is estimated between Zn2+ and DPA-TAM a

A selective fluorescent sensor for imaging Cd2+ in living cells

A selective sensor 1 for the fluorescent imaging of Cd2+ in living cells has been designed and synthesized based on an internal charge transfer (ICT) mechanism. It can distinguish Cd2+ from Zn2+ and can be used in both general fluorescence intensity microscopy and ratiometric fluorescence microscopy. Copyright

New Sensitive and Selective Chemical Sensors for Ni2+and Cu2+Ions: Insights into the Sensing Mechanism through DFT Methods

We report the synthesis and theoretical study of two new colorimetric chemosensors with special selectivity and sensitivity to Ni2+ and Cu2+ ions over other metal cations in the CH3CN/H2O solution. Compounds (E)-4-((2-nitrophenyl)diazenyl)-N,N-bis(pyridin-2-ylmethyl)aniline (A) and (E)-4-((3-nitrophenyl)diazenyl)-N,N-bis(pyridin-2-ylmethyl)aniline (B) exhibited a drastic color change from yellow to colorless, which allows the detection of the mentioned metal cations through different techniques. The interaction of sensors with these metal ions induced a new absorption band with a hypsochromic shift to the characteristic signal of the free sensors. A theoretical study via time-dependent density functional theory (TD-DFT) was performed. This method has enabled us to reproduce the hypsochromic shift in the maximum UV-vis absorption band and explain the selective sensing of the ions. For all of the systems studied, the absorption band is characterized by a π→ π? transition centered in the ligand. Instead of Ni2+ and Cu2+ ions, the transition is set toward the σ? molecular orbital with a strong contribution of the 3dx2-y2 transition (π→ 3dx2-y2). These absorptions imply a ligand-to-metal charge transfer (LMCT) mechanism that results in the hypsochromic shift in the absorption band of these systems.

Colorimetric indicators for specific recognition of Cu2+ and Hg2+ in physiological media: Effect of variations of signaling unit on optical response

Easy to synthesize probes are designed using bispicolyl moiety as the receptor unit with two different signaling moieties, anthraquinone and bisindolyl. Both the compounds show ‘naked-eye’ sensing of Cu2+ and Hg2+ in ～100% aqueous me

Effects of the Ligand Structure of Cu(II) Complexes on Oxidative DNA Cleavage

Cu complexes were synthesized by substituting the hydrogen of the amine group of basic ligand 2,2′-dipicoylamine (dpca) (complex 2) with CH3CO (complex 1), phenyl (complex 3), and methyl (complex 4), respectively, and their DNA cleavage activity was investigated using linear dichroism (LD) and electrophoresis. The DNA cleavage efficiencies of Cu complexes 3 and 4 with phenyl and methyl, which are electron-donating functional groups, turned out to be the highest, and LD magnitudes rapidly decreased at 260 nm. In particular, Cu complex 3 showed a rapid LD magnitude reduction to 63% of the total for 90 min, and to 50% of the total at 12 min. DNA cleavage efficiencies were high in the order of phenyl > methyl > HCH3CO, and the highest DNA cleavage efficiency was observed in the presence of electron-donating groups. The electrophoresis results are also consistent with the changes in LD spectra over time. The Cu complexes (1–4) were found to cleave DNA through oxidative pathways, and the major reaction oxygen species involved in DNA cleavage were the superoxide radical (·O2?), singlet oxygen (1O2), and hydroxyl radical (·OH).