30169-46-1

Upstream product

• 3815-34-7 2,2-dimethyl-1-phenyl-1,3-butanedione 

Downstream Products

• 112450-15-4 3,4,4-trimethyl-3,4-dihydro-3,5-diphenyl-2H-pyrazoles 
• 127958-29-6 Phenyl-(4,4,5,5-tetramethyl-3-phenyl-4,5-dihydro-pyrazol-1-yl)-methanone 
• 127958-33-2 4,4,5-Trimethyl-3,5-diphenyl-4,5-dihydro-pyrazole-1-carboxylic acid methyl ester 
• 127958-32-1 Phenyl-(4,4,5-trimethyl-3,5-diphenyl-4,5-dihydro-pyrazol-1-yl)-methanone 
• 1190831-15-2 4,4,5-trimethyl-3,5-diphenyl-1-(toluene-4-sulfonyl)-4,5-dihydro-1H-pyrazole 
• 1190831-14-1 4,4,5,5-tetramethyl-3-phenyl-1-(toluene-4-sulfonyl)-4,5-dihydro-1H-pyrazole 
• 91226-54-9 1,4,4-trimethyl-5-<2-(m-nitrophenyl)ethenyl>-3-phenyl-4H-pyrazolium iodide 
• 91226-55-0 1,4,4-Trimethyl-5-[(E)-2-(4-nitro-phenyl)-vinyl]-3-phenyl-4H-pyrazol-1-ium; iodide 
• 91226-56-1 5-[(E)-2-(2-Chloro-phenyl)-vinyl]-1,4,4-trimethyl-3-phenyl-4H-pyrazol-1-ium; iodide 
• 91226-57-2 1,4,4-Trimethyl-3-phenyl-5-((E)-styryl)-4H-pyrazol-1-ium; iodide 
• 91226-61-8 2,3,7,7a-tetrahydro-7,7-dimethyl-2(p-nitrophenyl)-7a-<2-(p-nitrophenyl)ethenyl>-6-phenylpyrazolo<5,1-b>oxazole 
• 91226-65-2 4,5-dihydro-1,4,4,5-tetramethyl-3-phenylpyrazole 
• 91226-51-6 1,4,4,5-Tetramethyl-3-phenyl-4H-pyrazol-1-ium; iodide 
• 127958-25-2 4,5-dihydro-4,4,5,5-tetramethyl-3-phenyl-1H-pyrazole 

Relevant academic research and scientific papers

Diastereo- and regioselective synthesis of diquinanes and related systems from tricyclo[3.3.0.02,4]octanes by chemical electron transfer (CET)

A new synthetic methodology for diquinanes by one-electron oxidation of tricyclo[3.3.0.02,4]octanes and subsequent stereocontrolled rearrangement is provided. The latter compounds are conveniently accessible through acid-catalyzed isopyrazole cycloaddition, followed by hydrogenation and photoextrusion of molecular nitrogen. The oxidative rearrangement of the tricyclooctanes proceeds catalytically and cleanly to afford regio- and diastereoselectively the corresponding diquinanes.

Synthesis of 4,4-Dimethyl-3,4-dihydro-3,3,5-trisubstituted-2H-pyrazoles and N-Benzoyl Derivatives: Method for "Hydrolysis" of Unreactive Amides and Carbamates

Addition of organolithium reagents to 4,4-dimethyl-3,5-disubstituted-4H-pyrazoles produced a series of 4,4-dimethyl-3,4-dihydro-3,3,5-trisubstituted-2H-pyrazoles, 2-6, in good yield.The reaction was stereoselective: addition of organolithium compounds occurred only to carbon-3 of 4,4-dimethyl-3-alkyl-5-aryl-4H-pyrazoles.The 3,4-dihydro-2H-pyrazoles were found to be of high sensitivity to oxygen.For long term storage and ease of handling, N-benzoyl derivatives were synthesized.Removal of protecting group could not be accomplished by use of many standard sets of conditions.Deprotection was accomplished in high yield by reaction of the N-benzoyl-4,4-dimethyl-3,4-dihydro-3,3,5-trisubstituted-2H-pyrazoles with anhydrous potassium t-butoxide in toluene in the presence of a phase transfer catalyst (18-Crown-6).Cleavage of a N-carbamate derivative was also achieved by this phase transfer approach.This methodology should be applicable to the hydrolysis of unreactive amides and carbamates in general.