301698-93-1 Usage
Explanation
The molecular formula represents the number of atoms of each element present in a molecule. In this case, the compound has 13 carbon (C) atoms, 16 hydrogen (H) atoms, 1 oxygen (O) atom, and 1 sulfur (S) atom.
Explanation
The compound is derived from a phenol, which is a hydroxylated aromatic ring. It has additional functional groups attached to the phenyl ring, making it a substituted phenol.
Explanation
The compound contains a hydroxy group, which is a functional group consisting of an oxygen atom bonded to a hydrogen atom (-OH). This group is known for its ability to form hydrogen bonds and participate in various chemical reactions.
Explanation
The compound has an alkyne group, which is a carbon-carbon triple bond (C≡C) followed by a hydrogen atom (-H). Alkynes are known for their reactivity and ability to undergo various chemical reactions, such as addition and substitution reactions.
Explanation
The compound contains a methylthio group, which is a sulfur atom bonded to a methyl group (-SCH3). This group can influence the compound's reactivity, stability, and potential biological activities.
Explanation
Due to its unique structure and functional groups, the compound has potential applications in the fields of organic synthesis and pharmaceuticals. It can be used as a building block for the synthesis of more complex molecules or as a starting material for the development of new drugs.
Explanation
Studies have shown that the compound may possess antioxidant and anti-inflammatory properties. These properties are important for the development of new drugs, as they can help protect cells from damage and reduce inflammation in the body.
Explanation
While the compound has shown promise in terms of its potential biological activities, more research is needed to fully understand its capabilities and how it can be best utilized in the fields of organic synthesis and pharmaceuticals.
Chemical structure
Substituted phenol derivative
Hydroxy group
-OH
Alkyne group
-C≡C-H
Methylthio group
-SCH3
Potential applications
Organic synthesis and pharmaceuticals
Biological activities
Antioxidant and anti-inflammatory properties
Further research needed
To fully understand its potential biological activities and applications
Check Digit Verification of cas no
The CAS Registry Mumber 301698-93-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,0,1,6,9 and 8 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 301698-93:
(8*3)+(7*0)+(6*1)+(5*6)+(4*9)+(3*8)+(2*9)+(1*3)=141
141 % 10 = 1
So 301698-93-1 is a valid CAS Registry Number.
301698-93-1Relevant articles and documents
Synthesis method of 5-bromo-2, 2-dimethyl-5-(4-methylsulfonylphenyl) furan-3 (2H)-one
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Paragraph 0040-0045; 0052-0055, (2020/07/13)
The invention discloses a synthesis method of 5-bromo-2, 2-dimethyl-5-(4-methylsulfonylphenyl) furan-3 (2H)-one, which belongs to the technical field of organic synthesis, and comprises the followingsteps: reacting 4-methylthiobenzaldehyde with a lithium
In Vitro Structure-Activity Relationship and in Vivo Studies for a Novel Class of Cyclooxygenase-2 Inhibitors: 5-Aryl-2,2-dialkyl-4-phenyl-3(2H)furanone Derivatives
Shin, Song Seok,Byun, Youngjoo,Lim, Kyung Min,Choi, Jin Kyu,Lee, Ki-Wha,Moh, Joo Hyun,Kim, Jin Kwan,Jeong, Yeon Su,Kim, Ji Young,Choi, Young Hoon,Koh, Hyun-Ju,Park, Young-Ho,Oh, Young Im,Noh, Min-Soo,Chung, Shin
, p. 792 - 804 (2007/10/03)
5-Aryl-2,2-dialkyl-4-phenyl-3(2H)furanone derivatives were studied as a novel class of selective cyclooxygenase-2 inhibitors with regard to synthesis, in vitro SAR, antiinflammatory activities, pharmacokinetic considerations, and gastric safety. If, a representative compound for methyl sulfone derivatives, showed a COX-2 IC50 comparable to that of rofecoxib. In case of 20b, a representative compound for sulfonamide derivatives, a potent antiinflammatory ED50 of 0.1 mg kg-1 day-1 was observed against adjuvant-induced arthritis by a preventive model, positioning 20b as one of the most potent COX-2 inhibitors ever reported. Furthermore, 20b showed strong analgesic activity as indicated by its ED50 of 0.25 mg/kg against carrageenan-induced thermal hyperalgesia in the Sprague-Dawley rat. 3(2H)Furanone derivatives showed due gastric safety profiles as selective COX-2 inhibitors upon 7-day repeat dosing. A highly potent COX-2 inhibitor of the 3(2H)furanone scaffold could be considered suitable for a future generation COX-2 selective arthritis medication with improved safety profiles.
4,5-diaryl-3(2H)-furanone derivatives as cyclooxygenase-2 inhibitors
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, (2008/06/13)
The present invention provides a novel class of 4,5-diaryl-3(2H)-furanone derivatives, which inhibit strongly and selectively COX-2 over COX-1. They are useful to treat inflammation, inflammation-associated disorders, and COX-2 mediated diseases.
2,2-dimethyl-4,5-diaryl-3(2H)furanone derivatives as selective cyclo-oxygenase-2 inhibitors
Shin, Song Seok,Noh, Min-Soo,Byun, Young Joo,Choi, Jin Kyu,Kim, Ji Young,Lim, Kyung Min,Ha, Jun-Yong,Kim, Jin Kwan,Lee, Chang Hoon,Chung, Shin
, p. 165 - 168 (2007/10/03)
A series of 2,2-dimethyl-5-{4-(methylsulfonyl)phenyl}-4-phenyl-3(2H)furanones was prepared and evaluated for their ability to inhibit cyclo-oxygenase-2 (COX-2).
