301823-97-2

Upstream product

• 58479-61-1 tert-butylchlorodiphenylsilane 
• 471269-86-0 (1R,2S,4R,5S)-5-hydroxy-3,3-dimethyl-1-[(2R*)-tetrahydropyran-2-yloxymethyl]-7-oxabicyclo[2.2.1]heptane-2-carboxylic acid ethyl ester 
• 301823-95-0 (+)-(1R,5S,7S)-6,6-dimethyl-10-oxa-3-azatricyclo[5.2.1.o^1,5]dec-8-en-4-one 
• 139437-47-1 (R)-2-{[1-Furan-2-yl-meth-(E)-ylidene]-amino}-2-phenyl-ethanol 
• 77704-39-3 (-)-(1R,5S,7S)-3-[(1R)-2-hydroxy-1-phenylethyl]-6,6-dimethyl-10-oxa-3-azatricyclo[5.2.1.0^1,5]dec-8-en-4-one 
• 77704-70-2 (-)-(R)-N-<(Furan-2-yl)methyl>-N-(2-hyydroxy-1-phenylethyl)-3-methylbut-2-enamid 
• 132168-60-6 (-)-(R)-2<<(Furan-2-yl)methyl>amino>-2-phenylethanol 
• 98-01-1 furfural 
• 110-87-2 3,4-dihydro-2H-pyran 
• 301823-96-1 (1R,2S,4S)-3,3-dimethyl-1-[(2R*)-tetrahydropyran-2-yloxymethyl]-7-oxabicyclo[2.2.1]hept-5-ene-2-carboxylic acid ethyl ester 
• 470690-19-8 (1R,2S,4S)-1-hydroxymethyl-3,3-dimethyl-7-oxabicyclo[2.2.1]hept-5-ene-2-carboxylic acid ethyl ester 

Downstream Products

• 301823-98-3 (+)-(S)-acetic acid [2-(tert-butyldimethylsilyloxymethyl)cyclohex-1-enyl][(1R,2S,4R,5S)-5-(tert-butyldiphenylsilyloxy)-3,3-dimethyl-2-vinyl-7-oxabicyclo[2.2.1]heptan-1-yl]methyl ester 
• 471270-02-7 (+)-(S)-[2-(tert-butyldimethylsilyloxymethyl)cyclohex-1-enyl][(1R,2S,4R,5S)-5-(tert-butyldiphenylsilyloxy)-3,3-dimethyl-2-vinyl-7-oxabicyclo[2.2.1]heptan-1-yl]methanol 
• 301824-00-0 C₃₆H₄₄O₆Si 
• 471270-17-4 C₃₅H₄₂O₆Si 
• 471270-03-8 (S)-acetic acid [(1R,2S,4R,5S)-5-(tert-butyldiphenylsilyloxy)-3,3-dimethyl-2-vinyl-7-oxabicyclo[2.2.1]heptan-1-yl](2-hydroxymethylcyclohex-1-enyl)methyl ester 
• 301823-99-4 C₃₅H₄₄O₆Si 
• 301823-92-7 (-)-(S)-acetic acid [(1R,2S,4R,5S)-5-(tert-butyldiphenylsilyloxy)-3,3-dimethyl-2-vinyl-7-oxabicyclo[2.2.1]heptan-1-yl](2-vinylcyclohex-1-enyl)methyl ester 
• 471270-09-4 (-)-(S)-acetic acid [(1R,2S,4R,5S)-5-(tert-butyldiphenylsilyloxy)-3,3-dimethyl-2-vinyl-7-oxabicyclo[2.2.1]heptan-1-yl](2-formylcyclohex-1-enyl)methyl ester 
• 471270-01-6 (+)-(S)-[(1R,2S,4R,5S)-5-(tert-butyldiphenylsilyloxy)-3,3-dimethyl-2-vinyl-7-oxabicyclo[2.2.1]heptan-1-yl](2-hydroxymethylcyclohex-1-enyl)methanol 
• 301823-93-8 (+)-(3S)-3-[(1R,2S,4R,5S)-5-(tert-butyldiphenylsilyloxy)-3,3-dimethyl-2-vinyl-7-oxabicyclo[2.2.1]heptan-1-yl]-4,5,6,7-tetrahydroisobenzofuran-1(3H)-one 
• 301823-91-6 C₃₅H₄₄O₄Si 
• 471913-18-5 acetic acid {2-(tert-butyl-dimethyl-silanyloxymethyl)-4-[2-(tert-butyl-diphenyl-silanyloxymethyl)-cyclopropylmethyl]-cyclohex-1-enyl}-[5-(tert-butyl-diphenyl-silanyloxy)-3,3-dimethyl-2-vinyl-7-oxa-bicyclo[2.2.1]hept-1-yl]-methyl ester 
• 471913-17-4 {2-(tert-butyl-dimethyl-silanyloxymethyl)-4-[2-(tert-butyl-diphenyl-silanyloxymethyl)-cyclopropylmethyl]-cyclohex-1-enyl}-[5-(tert-butyl-diphenyl-silanyloxy)-3,3-dimethyl-2-vinyl-7-oxa-bicyclo[2.2.1]hept-1-yl]-methanol 
• 471913-19-6 Acetic acid (S)-[(1R,2S,4R,5S)-5-(tert-butyl-diphenyl-silanyloxy)-3,3-dimethyl-2-vinyl-7-oxa-bicyclo[2.2.1]hept-1-yl]-{4-[2-(tert-butyl-diphenyl-silanyloxymethyl)-cyclopropylmethyl]-2-hydroxymethyl-cyclohex-1-enyl}-methyl ester 

Relevant academic research and scientific papers

Studies towards the total synthesis of solanoeclepin A: Synthesis and potato cyst nematode hatching activity of analogues containing the tetracyclic left-hand substructure

In our studies towards the total synthesis of solanoeclepin A, a natural hatching agent of potato cyst nematodes, three analogues containing the tetracyclic left-handed substructure have been synthesised. First, the synthesis of the parent tetracycle 2 in

Enantioselectve synthesis of the tetracyclic left-hand substructure of solanoeclepin A

The synthesis of the enantiopure left-hand substructure of solanoeclepin A is described. Key steps include a chromium-mediated coupling of an oxabicyclic aldehyde with a β-ketoester-derived enol triflate to give a lactone, and a ring-closing metathesis reaction to form the seven-membered ring.