301838-64-2

Upstream product

• 301838-58-4 {5-Benzyloxy-2-[(S)-2-(tert-butyl-dimethyl-silanyloxymethyl)-4-eth-(E)-ylidene-pyrrolidine-1-carbonyl]-4-methoxy-phenyl}-carbamic acid allyl ester 
• 60547-92-4 4-(benzyloxy)-5-methoxy-2-nitrobenzoic acid 
• 64154-78-5 4-benzyloxy-5-methoxy-2-nitrobenzoyl chloride 
• 64187-48-0 methyl (2S,4R)-1-benzyloxycarbonyl-4-hydroxypyrrolidine-2-carboxylate 
• 95687-41-5 (2S,4R)-N1-(benzyloxycarbonyl)-4-hydroxy-2-(hydroxymethyl)-pyrrolidine 
• 51-35-4 4R-4-hydroxyproline 
• 13504-85-3 (2S,4R)-1-(benzyloxycarbonyl)-4-hydroxypyrrolidine-2-carboxylic acid 
• 260417-68-3 {5-Benzyloxy-2-[(2S,4R)-2-(tert-butyl-dimethyl-silanyloxymethyl)-4-hydroxy-pyrrolidine-1-carbonyl]-4-methoxy-phenyl}-carbamic acid allyl ester 
• 260417-69-4 {5-benzyloxy-2-[2-(tert-butyl-dimethyl-silanyloxymethyl)-4-oxo-pyrrolidine-1-carbonyl]-4-methoxy-phenyl}-carbamic acid allyl ester 
• 260417-66-1 (4-Benzyloxy-5-methoxy-2-nitro-phenyl)-[(2S,4R)-2-(tert-butyl-dimethyl-silanyloxymethyl)-4-hydroxy-pyrrolidin-1-yl]-methanone 
• 260417-67-2 (2-Amino-4-benzyloxy-5-methoxy-phenyl)-[(2S,4R)-2-(tert-butyl-dimethyl-silanyloxymethyl)-4-hydroxy-pyrrolidin-1-yl]-methanone 
• 260417-93-4 benzyl (2S,4R)-2-(((tert-butyldimethylsilyl)oxy)methyl)-4-hydroxypyrrolidine-1-carboxylate 
• 260417-94-5 (2S,4R)-2-tert-butyldimethylsilyloxymethyl-4-hydroxypyrrolidine 

Relevant academic research and scientific papers

Effect of C2-exo unsaturation on the cytotoxicity and DNA-binding reactivity of pyrrolo[2,1-c][1,4]benzodiazepines

A series of novel C2-exo unsaturated pyrrolo[2,1-c][1,4]benzodiazepines (PBDs) has been synthesised via a versatile pro-C2 ketone precursor. C2-exo-unsaturation enhances both DNA-binding reactivity and in vitro cytotoxic potency. (C) 2000 Elsevier Science Ltd. All rights reserved.