301851-34-3

Basic information

• Product Name: (2R,3S,4R,1'R)-2-(tert-butyldiphenylsilyloxymethyl)-4-(2,2-dimethyl-[1,3]dioxolan-4-yl)-3,4-dihydroxy-5-oxotetrahydrofuran-3-[(tert-butyldiphenylsilyloxy)carbaldehyde oxime]
• Synonyms: (2R,3S,4R,1'R)-2-(tert-butyldiphenylsilyloxymethyl)-4-(2,2-dimethyl-[1,3]dioxolan-4-yl)-3,4-dihydroxy-5-oxotetrahydrofuran-3-[(tert-butyldiphenylsilyloxy)carbaldehyde oxime]
• CAS NO: 301851-34-3
• Molecular Weight: 768.067
• Mol File: 301851-34-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2R,3S,4R,1'R)-2-(tert-butyldiphenylsilyloxymethyl)-4-(2,2-dimethyl-[1,3]dioxolan-4-yl)-3,4-dihydroxy-5-oxotetrahydrofuran-3-[(tert-butyldiphenylsilyloxy)carbaldehyde oxime](CAS DataBase Reference)
• NIST Chemistry Reference: (2R,3S,4R,1'R)-2-(tert-butyldiphenylsilyloxymethyl)-4-(2,2-dimethyl-[1,3]dioxolan-4-yl)-3,4-dihydroxy-5-oxotetrahydrofuran-3-[(tert-butyldiphenylsilyloxy)carbaldehyde oxime](301851-34-3)
• EPA Substance Registry System: (2R,3S,4R,1'R)-2-(tert-butyldiphenylsilyloxymethyl)-4-(2,2-dimethyl-[1,3]dioxolan-4-yl)-3,4-dihydroxy-5-oxotetrahydrofuran-3-[(tert-butyldiphenylsilyloxy)carbaldehyde oxime](301851-34-3)

Safety Data

• Hazardous Substances Data: 301851-34-3(Hazardous Substances Data)

Upstream product

• 58479-61-1 tert-butylchlorodiphenylsilane 
• 218767-20-5 (2R,3S,4R,1'R)-4-(2,2-dimethyl-[1,3]dioxolan-4-yl)-3,4-dihydroxy-2-hydroxymethyl-5-oxotetrahydrofuran-3-carbaldehyde oxime 
• 218767-18-1 (2R,3S,1'R,1''R)-3,4-bis(2,2-dimethyl-[1,3]dioxolan-4-yl)-2,3-dihydroxy-4-(carbaldehyde oxime)butyric acid 
• 218767-17-0 (3R,4S,1'R,1''R)-3,4-bis(2,2-dimethyl-[1,3]dioxolan-4-yl)-3,4,5-trihydroxy-4,5-dihydrofuran-2-one 
• 218767-16-9 (1'S,1''S)-3,4-bis(2,2-dimethyl-[1,3]dioxolan-4-yl)-5-hydroxy-5H-furan-2-one 
• 218767-19-2 (2R,3S,4R,1'R)-4-(1,2-dihydroxyethyl)-3,4-dihydroxy-2-hydroxymethyl-5-oxotetrahydrofuran-3-carbaldehyde oxime 
• 218767-15-8 (1'S,1''S)-3,4-bis(2,2-dimethyl-(1,3)dioxolan-4-yl)furan 
• 218767-14-7 (1'S,1''S)-3,4-bis(1,2-dihydroxyethyl)furan 
• 189764-10-1 3,4-divinylfuran 
• 4282-33-1 dimethyl 3,4-furandicarboxylate 
• 7040-25-7 3,4-diformylfuran 
• 14496-24-3 3,4-bis(hydroxymethyl)furan 

Downstream Products

• 301851-37-6 (4R,5R,8R,9S)-8-(tert-butyldiphenylsilyloxymethyl)-9-hydroxy-2,2-dimethyl-6-oxo-4-(2-trimethylsilylethoxymethoxymethyl)-1,3,7-trioxa-spiro[4.4]nonane-9-[(tert-butyldiphenylsilyloxy)carbaldehyde oxime] 
• 301851-36-5 (2R,3S,4R,1'R)-2-(tert-butyldiphenylsilyloxymethyl)-3,4-dihydroxy-4-[1'-hydroxy-2'-(2-trimethylsilylethoxymethoxy)ethyl]-5-oxotetrahydrofuran-3-[(tert-butyldiphenylsilyloxy)carbaldehyde oxime] 
• 301851-35-4 (2R,3S,4R,1'R)-2-(tert-butyldiphenylsilyloxymethyl)-4-(1,2-dihydroxyethyl)-3,4-dihydroxy-5-oxotetrahydrofuran-3-[(tert-butyldiphenylsilyloxy)carbaldehyde oxime] 

Relevant articles and documents

A symmetry-based formal synthesis of zaragozic acid A

A symmetry-based strategy for the synthesis of the zaragozic acids is reported. Two enantioselective dihydroxylations were used to establish the absolute configuration of a C2 symmetric intermediate. Noteworthy transformations include a group-selective lactonization, which accomplished an end-differentiation of a pseudo-C2 symmetric intermediate. Late stage protecting group adjustments and oxidations accomplished a formal synthesis of zaragozic acid A.