30203-07-7Relevant academic research and scientific papers
Synthesis of some 3,6-disubstituted pyridazines
Shin, Mi-Seon,Kang, Young-Jin,Chung, Hyun-A.,Park, Jung-Won,Kweon, Deok-Heon,Lee, Woo Song,Yoon, Yong-Jin,Kim, Sung-Kyu
, p. 1135 - 1142 (1999)
Some novel 3-halo-6-(4-substituted-phenoxy)pyridazines and 3,6-di-(4- substituted-phenoxy)pyridazines were synthesized from 3,6-dichloropyridazine or 3,6-diiodopyridazine. 3,6-Diiodopyridazine was prepared from 3,6- dichloropyridazine using hydriodic acid/iodine monochloride.
COMPOUNDS AND METHODS FOR TREATING PROTEIN FOLDING DISORDERS
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Page/Page column 128, (2008/12/05)
The invention is directed to compounds and methods for treating protein folder disorders. In certain embodiments the invention provides compounds and methods for treating neurodegenerative diseases such as Alzheimer's disease, tauopathy, cerebral amyloid angiopathy, Lewy body disease, dementia, Huntington's disease and prion-based spongiform encelopathy. The invention further provides compounds, methods and pharmaceutical compositions for inhibiting tau protein, Aβ protein or α-synuclein protein aggregation.
