30222-03-8Relevant academic research and scientific papers
Retro-ene reactions in heterocyclic synthesis. V. A novel synthetic method for 1,3,5-triazine-2,4(1H,3H)-diones
Ito, Kunio,Sekiguchi, Chiharu,Miida, Asuka Wakai Hiroyuki,Ihara, Shogo
, p. 1533 - 1535 (2008/09/18)
(Chemical Equation Presented) N-t-Butylamidines 1 on heating with diphenyl carbonate (2) at 150-180° gave the 1,3,5-triazine-2,4(1H,3H)-dione derivatives 5. Acylation of amidines 1 and cyclocondensation of the resulting carbamates 3 gave [1,3,5,7]tetrazocine-2,6-dione derivatives 4, and subsequent retro-ene reaction and ring contraction afforded triazine derivatives 5.
Retro-ene reactions in heterocyclic synthesis. IV [1]. A new synthetic method for 6-hydroxypyrimidin-4(3H)-ones and 1,3,5-triazine-2,4(1H,3H)- diones
Ito, Kunio,Miyajima, Shingo
, p. 41 - 43 (2007/10/03)
N-t-Butylbenzamidines 1 reacted with diphenyl phenylmalonate or diphenyl methylmalonate to give 6-hydroxypyrimidin-4(3H)-ones 4 or 5. Amidines 1 on reaction with diphenyl imidodicarboxylate afforded 1,3,5-triazine-2,4(1H,3H)- diones 8.
