302589-19-1Relevant academic research and scientific papers
Covalent and noncovalent immobilization of Arylid-BOX ligands and their derivatives: Evaluation in the catalytic asymmetric cyclopropanation of styrenes
Carreiro, Elisabete P.,Moura, Nuno M. M.,Burke, Anthony J.
experimental part, p. 518 - 528 (2012/03/26)
The aim of this work was to immobilize an Arylid-BOX ligand on solid supports either by covalent attachment (to Wang resin) or by noncovalent attachment (on MK10 and SiO2) and to evaluate the products in the catalytic asymmetric cyclopropanatio
Synthesis and evaluation of methyl 2-methoxycarbonyl-3-phenylpropionate derivatives as a new type of angiotensin converting enzyme inhibitors
Cai, Xiao-Hua,Xie, Bing,Guo, Hui
, p. 1110 - 1113 (2007/10/03)
Methyl 2-methoxycarbonyl-3-phenylpropionate derivatives were prepared, and their inhibitory activities for angiotensin converting enzyme (ACE) were evaluated. Compounds 5b (IC50 = 0.0039 μmol/L), 5d (IC 50 = 0.0027 μmol/L), 5e (IC50 = 0.0021 μmol/L), and 5f (IC50 = 0.0052 μmol/L) exhibited more potent ACE inhibitiory activity than the control drug Captopril (IC50 = 0.0075 μmol/L).
Compounds, their preparation and use
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Example 1, (2008/06/13)
The present invention relates to compounds of the general formula (I) The compounds are useful in the treatment and/or prevention of conditions mediated by nuclear receptors, in particular the Peroxisome Proliferator-Activated Receptors (PPAR).
New compounds, their preparation and use
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, (2008/06/13)
The present invention relates to compounds of the general formula (I) The compounds are useful in the treatment and/or prevention of conditions mediated by nuclear receptors, in particular the Peroxisome Proliferator-Activated Receptors (PPAR).
