30264-74-5

Upstream product

• 932-96-7 N-methyl(p-chloroaniline) 
• 79-04-9 chloroacetyl chloride 

Downstream Products

• 64212-85-7 Thiophosphoric acid S-{[(4-chloro-phenyl)-methyl-carbamoyl]-methyl} ester O,O'-diethyl ester 
• 64213-62-3 Methyl-phosphonodithioic acid S-{[(4-chloro-phenyl)-methyl-carbamoyl]-methyl} ester O-ethyl ester 
• 64214-15-9 Isopropyl-thiophosphoramidic acid S-{[(4-chloro-phenyl)-methyl-carbamoyl]-methyl} ester O-ethyl ester 
• 1448363-10-7 2-azido-N-(4-chlorophenyl)-N-methylacetamide 
• 39203-70-8 2-amino-4'-chloro-N-methylacetanilide 
• 75945-62-9 4'-chloro-2-isocyno-N-methylacetanilide 
• 75945-61-8 2-formamido-4'-chloro-N-methylacetanilide 
• 75945-71-0 (4-Chloro-phenyl)-methyl-oxazol-5-yl-amine 
• 102235-97-2 4'-Chlor-N-methyl-2-(triphenylphosphoranyliden)acetanilid 
• 102235-73-4 4'-Chlor-N-methyl-1,2-propadien-1-carboxanilid 
• 102235-91-6 triphenylphosphoniumchlorid 
• 33280-19-2 N-phthalimide 

Relevant academic research and scientific papers

Photoinduced and N-bromosuccinimide-mediated cyclization of 2-azido-N-phenylacetamides

An efficient synthesis of quinoxalin-2(1H)-ones or spiro[cyclohexene-1, 2′-imidazol]-4′-ones has been achieved in moderate to high yields by the visible light-induced and N-bromosuccinimide-mediated cyclization reaction of 2-azido-N-phenylacetamides at ambient temperature. Both the regioselectivity and the speed of cyclization are affected by the substituents attached to the phenyl ring. For example, quinoxalin-2-ones are produced as the main products when the substrates bear electron-withdrawing groups at the para-position of the phenyl ring; in contrast, spiro[cyclohexene-1,2′-imidazol]-4′-ones are obtained as the main products when the substrates bear electron-donating groups at the para-position.

Cycloadditions, 7. Intramolecular Diels-Alder Reactions of Allenecarboxanilides; Variation of the Substituents in the p-Position of the Aniline Nucleus

The N-methyl-1,2-propadiene-1-carboxanilides 6a-h, differently substituted in the p-position, are synthesized by Wittig reaction of the carbamoylmethylenephosphoranes 5 with ketene.They isomerize by thermolysis in boiling xylene to give the tricycles 7a-h, the products of the intramolecular Diels-Alder reaction, and in some cases also to the quinolones 9, the products of a cyclization reaction.The order of the reaction and the influence of the substituents upon the rate of the intramolecular Diels -Alder reaction are determined by 1H-NMR spectroscopy.