30272-58-3

Upstream product

• 30239-74-8 2-ethyl-2-hydroxy-1-phenylbutan-1-one 
• 96-22-0 pentan-3-one 
• 1352617-34-5 2-ethyl-1-phenylbut-1-enyl t-butyldimethylsilyl ether 
• 5682-46-2 2-Ethylbutyrophenon 
• 627-21-4 2-Pentyne 
• 100-52-7 benzaldehyde 

Relevant academic research and scientific papers

Alkyne hydroacylation: Switching regioselectivity by tandem ruthenium catalysis

By using tandem Ru-catalysis, internal alkynes can be coupled with aldehydes for the synthesis of β,γ-unsaturated ketones. The catalyst promotes alkyne transformations with high regioselectivity, with examples that include the differentiation of a methyl vs ethyl substituent on the alkyne. Mechanistic studies suggest that the regioselectivity results from a selective allene formation that is governed by allylic strain.

Oxidative conversion of silyl enol ethers to α,β-unsaturated ketones employing oxoammonium salts

The oxidative conversion of silyl enol ethers to α,β-unsaturated ketones using a less-hindered class of oxoammonium salts (AZADO +BF4-) is described. The reaction proceeds via the ene-like addition of oxoammonium salts to silyl enol ethers.