302783-31-9Relevant academic research and scientific papers
3-Acyloxy-2-phenalkylpropyl amides and esters of homovanillic acid as novel vanilloid receptor agonists
Lee, Jeewoo,Park, Shin-Ung,Kim, Ji-Young,Kim, Jin-Kwan,Lee, Jiyoun,Oh, Uhtaek,Marquez, Victor E.,Beheshti, Maryam,Wang, Qiming J.,Modarres, Shayan,Blumberg, Peter M.
, p. 2909 - 2914 (1999)
A series of 3-acyloxy-2-phenalkylpropyl amides and esters of homovanillic acid were designed and synthesized as vanilloid receptor agonists containing the three principal pharmacophores of resiniferatoxin. Amide analogues 23, 5 and 11 were found to be potent agonists in vanilloid receptor assay both for ligand binding and for activation.
Facile chelation-controlled reductive opening of methoxybenzylidene acetals with Bu3SnH and MgBr2. Regioselective protection strategy as MPM ethers
Zheng,Yamauchi,Dei,Kusaka,Matsui,Yonemitsu
, p. 6441 - 6445 (2007/10/03)
A mild and efficient regioselective reductive opening of methoxybenzylidene acetals using a combination of Bu3SnH and MgBr2·OEt2, mainly via five-membered chelation intermediates is described. This reaction was applied to synthetic intermediates of myriaporon and tedanolide. (C) 2000 Elsevier Science Ltd.
