302808-10-2Relevant academic research and scientific papers
Synthesis and biocidal activity of some new 2-amino-4,6-diaryl-substituted-pyrimidines
Kothari,Singhal,Yijayvergia,Vyas,Verma
, p. 329 - 331 (2007/10/03)
The chalcones (3a-q), derived from 3,5-dibromo-4-hydroxyacetophenone (1a), 3,5-dibromo-2-hydroxyacetophenone (1b), 3-bromo-5-chloro-/5-methyl-2-hydroxyacetophenones (1c,d) and 4-(4'-nitrophenoxy)acetophenone (1c) and prepared by Claisen-Schmidt condensation with different substituted aromatic aldehydes (2a-f) in presence of base, on treatment with guanidine nitrate in ethanol and base give new 2-amino-4,6-diaryl-substituted-pyrimidines (4a-q). The compounds have been screened for their antibacterial and herbicidal activities.
