302839-10-7

Basic information

• Product Name: 2-bromo-1-(4-fluorophenyl)-2-(2-fluoropyridin-4-yl)ethanone
• Synonyms: 2-bromo-1-(4-fluorophenyl)-2-(2-fluoropyridin-4-yl)ethanone
• CAS NO: 302839-10-7
• Molecular Weight: 312.113
• Mol File: 302839-10-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-bromo-1-(4-fluorophenyl)-2-(2-fluoropyridin-4-yl)ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-bromo-1-(4-fluorophenyl)-2-(2-fluoropyridin-4-yl)ethanone(302839-10-7)
• EPA Substance Registry System: 2-bromo-1-(4-fluorophenyl)-2-(2-fluoropyridin-4-yl)ethanone(302839-10-7)

Safety Data

• Hazardous Substances Data: 302839-10-7(Hazardous Substances Data)

Upstream product

• 302839-09-4 1-(4-fluorophenyl)-2-(2-fluoropyridin-4-yl)ethan-1-one 

Downstream Products

• 868992-97-6 4-[4-(4-fluorophenyl)-2-piperidin-1-yl-1,3-oxazol-5-yl]pyridine-2(1H)-one 
• 868993-38-8 [4-(4-fluorophenyl)-5-(2-fluoropyridin-4-yl)-1,3-thiazol-2-yl](pyridin-3-yl)methanol 
• 1095708-26-1 2-(4-fluorophenyl)-3-(2-fluoropyrid-4-yl)-6-(4-methylpiperazin-1-yl)imidazo[1,2-b]pyridazine 
• 337902-75-7 4-(4-Fluorophenyl)-2-(1-ethoxycarbonylpiperidin-4-yl)-5-(2-fluoro-4-pyridinyl)thiazole 
• 1062606-47-6 C₁₉H₁₇F₂N₃O 
• 1062606-59-0 C₁₈H₁₆F₂N₄S 
• 742078-92-8 4-[4-(4-fluoro-phenyl)-5-[2-(1-phenyl-ethylamino)-pyridin-4-yl]-1-(2-trimethylsilanyl-ethoxymethyl)-1H-imidazol-2-yl]-1-methyl-piperidin-4-ol 
• 302839-17-4 4-[5-(2-cyclohexylamino-pyridin-4-yl)-4-(4-fluoro-phenyl)-oxazol-2-yl]-piperidine-1-carboxylic acid tert-butyl ester 
• 742078-86-0 4-[4-(4-fluoro-phenyl)-5-(2-fluoro-pyridin-4-yl)-1-(2-trimethylsilanyl-ethoxymethyl)-1H-imidazol-2-yl]-1-methyl-piperidin-4-ol 
• 337902-76-8 4-{4-(4-Fluoro-phenyl)-5-[2-((S)-1-phenyl-ethylamino)-pyridin-4-yl]-thiazol-2-yl}-piperidine-1-carboxylic acid ethyl ester 
• 337902-35-9 4-(4-Fluorophenyl)-2-(piperidin-4-yl).5-(2-(1-(S)-phenylethyl)amino-4-pyridinyl)thiazole 
• 302839-14-1 4-[4-(4-fluoro-phenyl)-5-(2-fluoro-pyridin-4-yl)-oxazol-2-yl]-piperidine-1-carboxylic acid tert-butyl ester 
• 742078-87-1 4-[4-(4-fluoro-phenyl)-5-(2-fluoro-pyridin-4-yl)-thiazol-2-yl]-1-methyl-piperidin-4-ol 
• 742078-82-6 2-fluoro-4-[5-(4-fluoro-phenyl)-3-(2-trimethylsilanyl-ethoxymethyl)-3H-imidazol-4-yl]-pyridine 

Relevant articles and documents

NEW SUBSTITUTED 1,3-THIAZOLE DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF HAVING IMMUNOSUPPRESSION AND INFLAMMATION INHIBITORY ACITIVITY, INTERMEDIATE COMPOUNDS OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, A PROCESS FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME

Disclosed relates to new substituted 1,3-thiazole derivatives or pharmaceutically acceptable salts thereof having immunosuppresion and inflammation inhibitory activity, intermediate compounds or pharmaceutically acceptable salts thereof, a process for the preparation thereof, and a pharmaceutical composition comprising the same. The compound of the present invention having excellent TNF-α inhibitory activity and inflammation inhibitory activity can be effectively used in the prevention and treatment of TNF-α related diseases.