302939-86-2

Basic information

• Product Name: 2-Bromo-6-methylquinoline
• Synonyms: Quinoline, 2-bromo-6-methyl-;2-Bromo-6-methylquinoline
• CAS NO: 302939-86-2
• Molecular Formula: C10H8BrN
• Molecular Weight: 222.08
• EINECS: -0
• Mol File: 302939-86-2.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 309.882 °C at 760 mmHg
• Flash Point: 141.212 °C
• Appearance: /
• Density: 1.488 g/cm³
• Vapor Pressure: 0.00113mmHg at 25°C
• Refractive Index: 1.654
• Storage Temp.: Room temperature.
• CAS DataBase Reference: 2-Bromo-6-methylquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Bromo-6-methylquinoline(302939-86-2)
• EPA Substance Registry System: 2-Bromo-6-methylquinoline(302939-86-2)

Safety Data

• Hazardous Substances Data: 302939-86-2(Hazardous Substances Data)

Usage

General Description

2-Bromo-6-methylquinoline is a heterocyclic compound with the molecular formula C10H8BrN. It is a substituted quinoline derivative that contains a bromine atom and a methyl group attached to the quinoline ring. This chemical is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It has also been studied for its potential use as a building block in organic synthesis reactions. 2-Bromo-6-methylquinoline is known for its versatile chemical properties, making it an important compound in the field of organic chemistry.

InChI:InChI=1/C10H8BrN/c1-7-2-4-9-8(6-7)3-5-10(11)12-9/h2-6H,1H3

Upstream product

• 91-62-3 6-methylquinoline 
• 29969-49-1 1,6-dimethyl-2(1H)-quinolinone 
• 4053-42-3 6-methylquinoline-N-oxide 
• 4053-34-3 6-methylquinolin-2(1H)-one 
• 134430-88-9 (2E)-N-(4-methylphenyl)-3-phenylprop-2-enamide 
• 106-49-0 p-toluidine 

Relevant articles and documents

Structure-based design and profiling of novel 17β-HSD14 inhibitors

The human enzyme 17β-hydroxysteroid dehydrogenase 14 (17β-HSD14) oxidizes the hydroxyl group at position 17 of estradiol and 5-androstenediol using NAD+ as cofactor. However, the physiological role of the enzyme remains unclear. We recently des

A highly practical and convenient halogenation of fused heterocyclic N-oxides

A novel, simple and practical method for the regioselective halogenation of fused heterocyclic N-oxides has been developed. It employs Vilsmeier reagent, generated in situ by POX3and DMF, as both the activating agent and the nucleophilic halide source. The method is amenable across a broad range of substrates, including quinolines, isoquinolines and the diazine N-oxides, possessing a variety of substitution patterns. Furthermore, all of the reagents associated are cheap and easy to obtain. The potential extension of this method to a one-pot oxidation/halogenation sequence that obviates the need for isolation of the N-oxide intermediates is also presented.

Quinoline carboxamide-type ABCG2 modulators: Indole and quinoline moieties as anilide replacements

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