302949-00-4

Basic information

• Product Name: 7-CHLORO-8-METHYL-4-OXO-1,4-DIHYDRO-QUINOLINE-3-CARBOXYLIC ACID
• Synonyms: AURORA 17786;7-CHLORO-8-METHYL-4-OXO-1,4-DIHYDRO-QUINOLINE-3-CARBOXYLIC ACID;OTAVA-BB BB0109080014;7-Chloro-8-methyl-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid
• CAS NO: 302949-00-4
• Molecular Formula: C11H8ClNO3
• Molecular Weight: 237.64
• Mol File: 302949-00-4.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 409.0±45.0 °C(Predicted)
• Appearance: /
• Density: 1.480±0.06 g/cm3(Predicted)
• PKA: 5.96±0.70(Predicted)
• CAS DataBase Reference: 7-CHLORO-8-METHYL-4-OXO-1,4-DIHYDRO-QUINOLINE-3-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 7-CHLORO-8-METHYL-4-OXO-1,4-DIHYDRO-QUINOLINE-3-CARBOXYLIC ACID(302949-00-4)
• EPA Substance Registry System: 7-CHLORO-8-METHYL-4-OXO-1,4-DIHYDRO-QUINOLINE-3-CARBOXYLIC ACID(302949-00-4)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 22
• HazardClass: IRRITANT
• Hazardous Substances Data: 302949-00-4(Hazardous Substances Data)

Upstream product

• 87-60-5 3-chloro-2-methylbenzenamine 
• 58666-10-7 2-[(3-chloro-2-methyl-phenylamino)-methylene]-malonic acid diethyl ester 
• 5350-94-7 7-chloro-8-methyl-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid ethyl ester 

Relevant articles and documents

Investigations on the 4-quinolone-3-carboxylic acid motif. 2. Synthesis and structure-activity relationship of potent and selective cannabinoid-2 receptor agonists endowed with analgesic activity in vivo

Quinolone-3-carboxamides 11 bearing at position 5, 6, 7, or 8 diverse substituents such as halides, alkyl, aryl, alkoxy, and aryloxy groups differing in their steric/electronic properties, were prepared. The new compounds were tested in vitro for CB1 and