302968-98-5Relevant academic research and scientific papers
First synthesis and pharmacological evaluation of benzoindolizidine and benzoquinolizidine analogues of α- and β-peltatin
Couture, Axel,Deniau, Eric,Grandclaudon, Pierre,Lebrun, Stephane,Leonce, Stephane,Renard, Pierre,Pfeiffer, Bruno
, p. 2113 - 2125 (2007/10/03)
The benzoindolizidine and-quinolizidine analogues of α- and β-peltatin were designed and synthesized by two different synthetic routes involving as the key step the Bischler-Napieralski cyclization of suitably substituted N-acyl-2-arylmethylpyrrolidine and -piperidine derivatives. The in vitro biological activity of these analogues as well as some of their derivatives was subsequently evaluated. Copyright (C) 2000 Elsevier Science Ltd.
