303-95-7

Basic information

• Product Name: ubiquinone 7
• Synonyms: ubiquinone 7;2,5-Cyclohexadiene-1,4-dione, 2-((2E,6E,10E,14E,18E,22E)-3,7,11,15,19,23,27-heptamethyl-2,6,10,14,18,22,26-octacosaheptaenyl)-5,6-dimethoxy-3-methyl-;2,5-Cyclohexadiene-1,4-dione, 2-(3,7,11,15,19,23,27-heptamethyl-2,6,10,14,18,22,26-octacosaheptenyl)-5,6-dimethoxy-3-methyl-, (all-E)-;Brn 2406878;Coenzyme Q7 (6ci);Coq7;Ubiquinone 35;Ubiquinone Q7
• CAS NO: 303-95-7
• Molecular Formula: C₄₄H₆₆O₄
• Molecular Weight: 659.001
• Product Categories: Fatty Acid Derivatives & Lipids;Glycerols;Glycerols, Fatty Acid Derivatives & Lipids
• Mol File: 303-95-7.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Storage Temp.: -20°C
• CAS DataBase Reference: ubiquinone 7(CAS DataBase Reference)
• NIST Chemistry Reference: ubiquinone 7(303-95-7)
• EPA Substance Registry System: ubiquinone 7(303-95-7)

Safety Data

• Hazardous Substances Data: 303-95-7(Hazardous Substances Data)

Usage

Uses

An isoprenoid quinone that siginificantly reduced blood sugar and ketone bodies of diabetics. It has been shown to decrease high blood citrate level in humans with periodontal disease. It is a viable therapeutic agent for muscular dystrophy.

Definition

ChEBI: A compound whose structure comprises a 2,3-dimethoxy-5-methylbenzoquinone nucleus, common to ubiquinones; and a side chain of seven isoprenoid units.

InChI:InChI=1/C44H66O4/c1-32(2)18-12-19-33(3)20-13-21-34(4)22-14-23-35(5)24-15-25-36(6)26-16-27-37(7)28-17-29-38(8)30-31-40-39(9)41(45)43(47-10)44(48-11)42(40)46/h18,20,22,24,26,28,30H,12-17,19,21,23,25,27,29,31H2,1-11H3/b33-20+,34-22+,35-24+,36-26+,37-28+,38-30+

Upstream product

• 257885-57-7 [(5E,9E,13E,17E,21E)-6,10,14,18,22,26-Hexamethyl-12-(toluene-4-sulfonyl)-heptacosa-5,9,13,17,21,25-hexaen-1-ynyl]-trimethyl-silane 
• 257885-65-7 ((5E,9E,13E,17E,21E)-6,10,14,18,22,26-Hexamethyl-heptacosa-5,9,13,17,21,25-hexaen-1-ynyl)-trimethyl-silane 
• 257885-53-3 (2E,6E)-2,6-Dimethyl-4-(toluene-4-sulfonyl)-11-trimethylsilanyl-undeca-2,6-dien-10-yn-1-ol 
• 257885-55-5 ((5E,9E)-11-Chloro-6,10-dimethyl-undeca-5,9-dien-1-ynyl)-trimethyl-silane 
• 257885-54-4 (2E,6E)-2,6-Dimethyl-11-trimethylsilanyl-undeca-2,6-dien-10-yn-1-ol 
• 257885-52-2 E-2-methyl-4-(p-toluenesulfonyl)-2-butenol 
• 257885-43-1 E-2-methyl-7-trimethylsilyl-2-buten-6-yn-1-ol 
• 257885-62-4 Z-2-methyl-7-trimethylsilyl-2-buten-6-yn-1-ol 
• 257885-47-5 E-1-chloro-2-methyl-7-trimethylsilyl-2-buten-6-yne 
• 257885-44-2 E-2-methyl-7-trimethylsilyl-2-buten-6-yn-1-al 
• 1838-94-4 isoprene epoxide 
• 68690-47-1 1-methyl-4-{[(2E,6E,10E)-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraen-1-yl]sulfonyl}benzene 
• 129746-03-8 (E)-4-(Tetrahydropyran-2-yloxy)-3-methylbut-2-enylchloride 
• 68799-82-6 1-chloro-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraene 

Downstream Products

• 484-59-3 reduced coenzyme Q₇ 
• 69060-01-1 Ubichinol-7-dibenzylether 
• 24904-69-6 trans-γ-Methoxy-isoubichinon-7 
• 74075-00-6 ubiquinol-8 
• 75426-26-5 ubiquinol 
• 24904-67-4 γ-Aethoxy-perhydro-ubichinon-7 
• 24904-66-3 γ-Methoxy-perhydro-ubichinon-7 
• 69060-02-2 (6E,10E,14E,18E,22E,26E)-28-(2,5-Bis-benzyloxy-3,4-dimethoxy-6-methyl-phenyl)-3-bromo-2,6,10,14,18,22,26-heptamethyl-octacosa-6,10,14,18,22,26-hexaen-2-ol 
• 81112-33-6 Ubihydrochinon-⁽³⁵⁾-diacetat 
• 28111-39-9 trans-γ-Hydroperoxy-isoubichinon-7 
• 24989-52-4 trans-γ-Hydroxy-isoubichinon-7 
• 24904-71-0 trans-γ-Aethoxy-isoubichinon-7 
• 5677-54-3 ubiquinone-9 

Relevant articles and documents

A convergent approach to coenzyme Q

Syntheses of coenzyme Q3-8 are described, as well as related systems such as plastoquinone-5. Preparation of the higher homologues of the ubiquinones relies on two new conjunctive reagents, or "linchpins", each of which ultimately corresponds to two or three prenyl units. These allow for attachment of a polyprenyl halide at one end, followed by a Ni(0)-catalyzed cross-coupling at the other terminus with a chloromethylated p-quinone.

PHOTOCHEMICAL REACTION OF UBIQUINONE (35). I. FORMATION OF

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