303133-46-2

Upstream product

• 771-60-8 2,3,4,5,6-pentafluoroaniline 
• 3282-30-2 pivaloyl chloride 

Downstream Products

• 1232326-96-3 C₁₈H₂₀F₅NO₃ 
• 1232327-00-2 C₂₀H₂₄F₅NO₃ 
• 1217507-36-2 benzyl 2-(4,4-dimethyl-5-oxo-1-(perfluorophenyl)pyrrolidin-2-yl)acetate 
• 1232326-15-6 C₁₅H₁₄F₅NO₃ 
• 1232326-25-8 C₁₆H₁₆F₅NO₃ 
• 1240020-46-5 C₁₇H₁₄F₅NO 
• 1240020-47-6 C₂₃H₁₈F₅NO 
• 1240020-48-7 C₂₉H₂₂F₅NO 

Relevant academic research and scientific papers

Palladium-catalyzed coupling of polyfluorinated arenes with heteroarenes via C-F/C-H activation

The first palladium-catalyzed coupling of 2-pyridyl-polyfluoroarenes and benzoxazole, thiazole, benzothiazole, benzoimidazole, oxazole or oxadiazole via a concurrent C-F/C-H activation is described. Initial mechanistic studies showed that C-F activation o

Pd(ll)-Catalyzed olefination of sp3 C-H bonds

"Chemical equation presented" The first Pd(II)-catalyzed sp3 C-H olefination reaction has been developed using N-arylamide directing groups. Following olefination, the resulting intermediates were found to undergo rapid 1,4-addition to give the corresponding &-lactams. Notably, this method was effective with substrates containing (-hydrogen atoms and could be applied to effect methylene C-H olefination of cyclopropane substrates.

Amide-directed arylation of sp3 C-H bonds using Pd(II) and Pd(0) catalysts

Protocols to effect β-arylation of sp3 C-H bonds via Pd(II)/(IV) and Pd(0)/(II) catalytic cycles have been achieved using a newly developed monodentate CONHC6F5 directing group. These reactions provide an unprecedented means to functionalize sp3 C-H bonds in aliphatic carboxylic acid-derived substrates.