303186-20-1

Basic information

• Product Name: 4-*difluoro(3,4,5-trifluorophenoxy)-methyl]-3,5-difluoro-4'-propyl-1,1'-biphenyl
• Synonyms: 4-*difluoro(3,4,5-trifluorophenoxy)-methyl]-3,5-difluoro-4'-propyl-1,1'-biphenyl;4-[Difluoro(3,4,5-trifluorophenoxy)Methyl]-3,5-difluoro-4'-n-propylbiphenyl, 99%;3,5-Difluoro-4'-propyl-4-((3,4,5-trifluorophenoxy)difluoromethyl)biphenyl;3-BB(F,F)XB(F,F)-F;PGQU 3F;PUQU 3F;(3,5-difluoro-4'-propylbiphenyl-4-yl)(difluoro)methyl 3,4,5-trifluorophenyl ether;(3,5-difluoro-4'-propylbiphenyl-4-yl)(difluoro)methyl
• CAS NO: 303186-20-1
• Molecular Formula: C22H15F7O
• Molecular Weight: 428.3427224
• Mol File: 303186-20-1.mol
• Article Data: 4

Chemical Properties

• Melting Point: 42.511℃ (acetic acid )
• Boiling Point: 431.6±45.0 °C(Predicted)
• Appearance: /
• Density: 1.332±0.06 g/cm3(Predicted)
• Vapor Pressure: 0.013-0.29Pa at 20-50℃
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: soluble in Methanol
• CAS DataBase Reference: 4-*difluoro(3,4,5-trifluorophenoxy)-methyl]-3,5-difluoro-4'-propyl-1,1'-biphenyl(CAS DataBase Reference)
• NIST Chemistry Reference: 4-*difluoro(3,4,5-trifluorophenoxy)-methyl]-3,5-difluoro-4'-propyl-1,1'-biphenyl(303186-20-1)
• EPA Substance Registry System: 4-*difluoro(3,4,5-trifluorophenoxy)-methyl]-3,5-difluoro-4'-propyl-1,1'-biphenyl(303186-20-1)

Safety Data

• Hazardous Substances Data: 303186-20-1(Hazardous Substances Data)

Usage

Chemical Properties

White Crystalline

Uses

4-*difluoro(3,4,5-trifluorophenoxy)-methyl]-3,5-difluoro-4'-propyl-1,1'-biphenyl is a liquid crystal with a difluoromethyleneoxy linkage group for active-matrix displays

Preparation

The preparation of?4-*difluoro(3,4,5-trifluorophenoxy)-methyl]-3,5-difluoro-4'-propyl-1,1'-biphenyl is as follows:In a fluororesin container 3,5-Difluoro-4'-propylbiphenyl-4-thionocarboxylic acid 3,4,5-trifluorophenyl ester (1.65 g, 3.9 mmol), ethyl acetate (10 mL) was added, Further, iodine pentafluoride (IF 5) (0.86 g, 3.9 mmol),And triethylamine · trihydrofluoride salt (NEt3 - 3HF)(0.62 g, 3.9 mmol), and the mixture was stirred at 65 ° C. for 6 hours. After stopping the reaction with an alkali, the organic layer was distilled off under reduced pressure, and the residue was purified by silica gel column chromatography and recrystallization to obtainTo obtain 4- [difluoro- (3,4,5-trifluorophenoxy) -methyl] -3,5-difluoro-4'-propylbiphenyl (1.50 g, 3.5 mmol). The isolation yield was 90%, and the purity was 99.88%.

Upstream product

• 1579306-03-8 3,5-difluoro-4'-propylbiphenyl-4-thionocarboxylic acid 3,4,5-trifluorophenyl ester 
• 1579306-11-8 4-chloro-2,6-difluorothionobenzoic acid 3,4,5-trifluorophenyl ester 
• 1435-43-4 1-chloro-3,5-difluorobenzene 
• 685563-69-3 {4-[difluoro(3,4,5-trifluorophenoxy)methyl]-3,5-difluorophenyl}boronic acid 
• 588-93-2 p-bromo-n-propylbenzene 
• 134150-01-9 4-propylphenylboric acid 
• 137528-87-1 3,5-difluoro-4'-propylbiphenyl 
• 99627-05-1 3,4,5-trifluorophenol 
• 595607-78-6 4-(bromodifluoromethyl)-3,5-difluoro-4'-propyl-1,1'-biphenyl 
• 959586-39-1 3,4,5-trifluorophenylchlorothionoformate 
• 461-96-1 3,5-difluorobromobenzene 
• 511540-64-0 4-[difluoro-(3,4,5-trifluorophenoxy)methyl]-1-bromo-3,5-difluorobenzene 

Relevant articles and documents

oxygen ether bridge bond containing two difluoromethane (CF 2 O) of the method for the preparation of monomer liquid crystal compound

The invention provides a preparation method of a CF2O-contained monomer liquid crystal compound. The preparation method comprises the following steps of (1) with a compound with a structure as shown in the formula I as a raw material, reacting under the catalytic action of a zinc reagent and copper salt and in the existence of a solvent to generate a compound with a structure as shown in the formula II; (2) enabling the compound with the structure as shown in the formula II and a fluorinated reagent to be subjected to fluoridation in the existence of the solvent to generate a compound with a structure as shown in the formula III; (3) enabling the compound with the structure as shown in the formula III and boric acid as shown in the formula IV to be subjected to SUZUKI coupled reaction in the existence of the solvent to obtain the CF2O-contained monomer liquid crystal compound with a structure as shown in the formula V, wherein the CF2O-contained monomer liquid crystal compound with a structure as shown in the formula V is as shown in the specification.

LIQUID CRYSTAL COMPOUND HAVING DIFLUOROPROPENYLENEOXY BONDING GROUP

The invention provides a liquid crystal compound having general physical properties necessary for the compound, namely stability to heat, light and so forth, a wide temperature range of a liquid crystal phase, a high clearing point, a good compatibility w