30336-09-5

Basic information

• Product Name: 5-hydroxy-3,4,5-triphenylfuran-2(5H)-one
• CAS NO: 30336-09-5
• Molecular Formula: C₂₂H₁₆O₃
• Molecular Weight: 328.3606
• Mol File: 30336-09-5.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 558.9°C at 760 mmHg
• Flash Point: 234.8°C
• Density: 1.295g/cm³
• Vapor Pressure: 2.49E-13mmHg at 25°C
• Refractive Index: 1.669
• CAS DataBase Reference: 5-hydroxy-3,4,5-triphenylfuran-2(5H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-hydroxy-3,4,5-triphenylfuran-2(5H)-one(30336-09-5)
• EPA Substance Registry System: 5-hydroxy-3,4,5-triphenylfuran-2(5H)-one(30336-09-5)

Safety Data

• Hazardous Substances Data: 30336-09-5(Hazardous Substances Data)

Usage

Chemical Structure

Contains a furanone core structure

Properties

Antioxidant and anti-inflammatory

Source

Found in various plants

Pharmaceutical Potential

Studied for anticancer and antimicrobial properties

Interest

Subject of further study for potential applications in medicine and drug development

Upstream product

• 501-65-5 diphenyl acetylene 
• 611-73-4 Benzoylformic acid 
• 7404-46-8 2,3,4-triphenyl-2-buten-4-olide 
• 100-52-7 benzaldehyde 
• 30563-76-9 (Z)-3-Benzoyl-2,3-diphenylacrylic acid 
• 79255-64-4 5-(Benzoyloxy)-3,4,5-triphenyl-1-oxacyclopent-3-en-2-one 

Downstream Products

• 30563-76-9 (Z)-3-Benzoyl-2,3-diphenylacrylic acid 
• 30341-84-5 trans-3-Benzoyl-2,3-diphenyl-acrylsaeure-methylester 
• 22245-45-0 3-hydroxy-3-phenyl-3H-phenanthro[9,10-c]furan-1-one 
• 30341-87-8 trans-3-Benzoyl-2,3-diphenyl-acrylsaeure 

Relevant articles and documents

Synthesis of highly substituted γ-hydroxybutenolides through the annulation of keto acids with alkynes and subsequent hydroxyl transposition

An efficient synthesis of highly functionalized γ-hydroxybutenolides through BF3-catalyzed annulation of keto acids with alkynes is described. Many advantages such as the use of routine reagents, easy operation, and a 100% atom efficiency are demonstrated in the method. The reaction can be readily scaled up to gram quantities, offering good practicality.

Intermolecular [2+2+1] Carbonylative Cycloaddition of Aldehydes with Alkynes, and Subsequent Oxidation to γ-Hydroxybutenolides by a Supported Ruthenium Catalyst

Intermolecular [2+2+1] carbonylative cycloaddition of aldehydes with alkynes and subsequent oxidation to γ-hydroxybutenolides is achieved using a supported ruthenium catalyst. A ceria-supported ruthenium catalyst promotes the reaction efficiently, even with an ambient pressure of CO or without external CO, thus giving the corresponding γ-hydroxybutenolide derivatives in good to high yields. Moreover this catalyst can be reused with no loss of activity.

Ozonolysis of Tetraphenylcyclopentadienone

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