30365-25-4Relevant academic research and scientific papers
TEMPO-mediated aliphatic C-H Oxidation with Oximes and hydrazones
Zhu, Xu,Wang, Yi-Feng,Ren, Wei,Zhang, Feng-Lian,Chiba, Shunsuke
supporting information, p. 3214 - 3217 (2013/07/26)
A method for aliphatic C-H bond oxidation of oximes and hydrazones mediated by 2,2,6,6-tetramethylpiperidin-1-oxyl (TEMPO) has been developed, which enables the concise assembly of substituted isoxazole and pyrazole skeletons.
Copper-catalyzed rearrangement of N-aryl nitrones into epoxyketimines
Mo, Dong-Liang,Anderson, Laura L.
supporting information, p. 6722 - 6725 (2013/07/26)
Please pass the oxygen: A new method for the preparation of trans-α,β-epoxyketimines has been achieved through a copper-catalyzed rearrangement of (E)-α,β-unsaturated nitrones. The scope and tolerance of the method is evaluated and the synthetic utility of the products is demonstrated. The new transformation provides facile access to an unusual, densely functionalized intermediate that can be exploited for further synthetic application. Copyright
A simple, modular synthesis of substituted pyridines
Liu, Songbai,Liebeskind, Lanny S.
, p. 6918 - 6919 (2008/09/21)
A simple, modular method to prepare highly substituted pyridines is disclosed. The method employs a cascade reaction comprising (1) a novel N-iminative, Cu-catalyzed cross-coupling of alkenylboronic acids at the N-O bond of α,β-unsaturated ketoxime O-pentafluorobenzoates, (2) electrocyclization of the resulting 3-azatriene, and (3) air oxidation affording highly substituted pyridines in moderate to excellent isolated yields (43-91%). Starting materials are readily available, and functional group tolerance is very good. Copyright
Convenient synthesis of 3,5-disubstituted isoxazoles
Kurangi, Reshma F.,Kawthankar, Rima,Sawal, Sulfala,Desai, Vidya G.,Tilve, Santosh G.
, p. 587 - 589 (2007/10/03)
α,β-Unsaturated oximes obtained from the corresponding α,β-unsaturated ketones on treatment with 2 equivalents of manganese dioxide in refluxing chloroform gives 3,5-disubstituted isoxazoles in good yields. Copyright Taylor & Francis Group, LLC.
REACTIVITY OF CARBONYL-CONTAINING DERIVATIVES OF 1-MONO- AND 1,3-DIPHENYLPROPANES. I. KINETICS OF THE OXIMATION REACTION OF FURANOCHROMONE, DIHYDROFLAVONONE, AND CHALCONE DERIVATIVES
Levashova, I. G.,Kazarinov, N. A.,Komissarenko, N. F.,Nel'zeva, L. B.
, p. 57 - 62 (2007/10/02)
The rate constants of the oximation reaction of more than twenty compounds belonging to the 1-mono and 1,3-diphenylpropane derivatives, and their activation energies have been determined.The oximation reaction depends on the structure and position of the
NMR spectra of trans-chalcone oxime, semicarbazone and thiosemicarbazone and their cyclic isomers (3,5-diphenyl-2-isoxazoline and 1-substituted 3,5-diphenyl-2-pyrazolines)
Balaban,Zugravescu,Avramovici,Silhan
, p. 704 - 708 (2007/10/04)
Earlier tentatively assigned structures for trans-chalcone oxime, semicarbazone and thiosemicarbazone, resp., have been corrected by means of NMR spectra: open-chain structures have been found for the title compounds formed in the acid catalyzed reaction, whereas basic catalysts lead to intramolecular cyclization with formation of 3,5-diphenyl-2-isoxazoline and 1-substituted 3,5-diphenyl-2-pyrazolines resp. Assignments in the NMR spectra were made by comparison with those from authentic samples of trans-dypnone and its semicarbazone.
