2183-27-9

Usage

Type of compound

Pyrazole derivative

Structure

Three phenyl groups attached to the pyrazole ring

Common use

Organic synthesis reactions

Thermal stability

High

Application in chemistry

Ligand in coordination chemistry

Potential applications

Pharmaceuticals, agrochemicals, and materials science

Role in photochemical reactions

Studied for its potential

Use as a photoinitiator

In polymerization processes

Upstream product

• 5411-12-1 chalcone epoxide 
• 64-19-7 acetic acid 
• 100-63-0 phenylhydrazine 
• 742-01-8 1,3,5-triphenyl-4,5-dihydro-1H-pyrazole 
• 64-17-5 ethanol 
• 16619-57-1 2-chloro-1,3-diphenylpropanone 
• 110-86-1 pyridine 
• 6372-57-2 (2S*,3S*)-2-benzoyl-1-benzyl-3-(phenyl)azidridine 
• 73305-97-2 2,3,5-triphenyl-2H-[1,2,6]thiadiazine 1-oxide 
• 71115-31-6 3-imino-1,3,N-triphenylprop-1-enylamine 
• 742-01-8 C₂₁H₁₈N₂⁽¹⁺⁾ 
• 93-58-3 benzoic acid methyl ester 
• 583-11-9 N-(1-phenylethylidene)phenylhydrazine 
• 7338-94-5 1,3-diphenyl-2-propynone 

Downstream Products

• 53608-37-0 phenyl(1,3,5-triphenyl-1H-pyrazol-4-yl)methanone 
• 26429-75-4 1-methyl-2,3,5-triphenyl-pyrazolium; iodide 
• 742-01-8 1,3,5-triphenyl-4,5-dihydro-1H-pyrazole 
• 143032-08-0 4-bromo-1,3,5-triphenyl-1H-pyrazole 
• 40697-44-7 4-nitroso-1,3,5-triphenyl-1H-pyrazole 
• 95223-16-8 1,3,5-triphenyl-1H-pyrazole-4-carbonyl chloride 
• 102183-30-2 1,2,5-tri-(4-nitrophenyl)-1H-pyrazole 
• 628333-86-8 1-(2-di-tert-butylphosphinophenyl)-3,5-diphenyl-1H-pyrazole 
• 628333-84-6 1-(2-di-isopropylphosphinophenyl)-3,5-diphenyl-1H-pyrazole 
• 143032-07-9 Benzenesulfonyl-(1,3,5-triphenyl-1H-pyrazol-4-yl)-acetonitrile 
• 53685-84-0 1,3,5-triphenyl-1H-pyrazole-4-carboxylic acid 
• 114824-59-8 trans-dichlorobis{1,3,5-triphenylpyrazole}palladium(II) 
• 1323293-44-2 4-chloro-1,3,5-triphenyl-1H-pyrazole 
• 1387506-58-2 4-chloro-2-methyl-1,3,5-triphenyl-1H-pyrazol-2-ium tetrafluoroborate 

Relevant academic research and scientific papers

Oxone?-promoted one-pot synthesis of 1-aryl-4-(organylselanyl)-1H-pyrazoles

We describe herein an efficient protocol for the one-pot synthesis of 4-organylselanylpyrazoles by direct cyclocondensation and C-H bond selenylation reactions starting from hydrazines, 1,3-diketones and diorganyl diselenides promoted by Oxone?

Microwave-assisted aromatization of 1,3,5-trisubstituted 2-pyrazolines by silica-supported N-bromosuccinimide as a useful reagent under solvent free 'dry' condition

An efficient aromatization of 1,3,5-trisubstituted 2-pyrazolines to theircorresponding pyrazoles by NBS was carried out under microwave irradiation and solvent-free conditions in moderate yields. It has also been observed that, by activating the NBS reage

N,N′,N,N′-tetrabromo-benzene-1,3-disulfonylamide as a novel reagent for oxidative aromatization of 1,3,5-trisubstituted pyrazolines under heterogeneous and solvent-free conditions

1,3,5-Trisubstituted pyrazolines were converted to the corresponding pyrazoles in good yields under heterogeneous and solvent-free conditions by N,N′,N,N′-tetrabromo-benzene-1,3-disulfonylamide [TBBDA] at ambient temperature.

Mild oxidation of 1,3,5-trisubstituted pyrazolines with N-bromo-sulphonamides

1,3,5-Trisubstituted pyrazolines to pyrazoles are carried out efficiently in the presence of new reagents N,N,N′,N′-tetrabromo-benzene-1,3- disulfonylamine [TBBDA] and N,N′-dibromo-N,N′-1,2-ethanediylbis-(p- toluenesulphonamide) [BNBTS] in solvent-free conditions with catalytic amounts of SiO2 under microwave irradiation in high yields.

Trichloroisocyanuric acid as a novel oxidizing agent for the oxidation of 1,3,5-trisubstituted pyrazolines under both heterogeneous and solvent free conditions

Trichloroisocyanuric acid is used as an effective oxidizing agent for the oxidation of 1,3,5-trisubstituted pyrazolines to their corresponding pyrazoles under both heterogeneous and also solvent free conditions with good yields at room temperature.

4-(p-Chloro)phenyl-1,2,4-triazole-3,5-dione as a novel and reusable reagent for the oxidation of 1,3,5-trisubstituted pyrazolines under mild conditions

4-(p-Chloro)phenyl-1,3,4-triazole-3,5-dione is used as an effective oxidizing agent for the oxidation of 1,3,5-trisubstituted pyrazolines to their corresponding pyrazoles under mild conditions with moderate to good yields at room temperature.

Silica-supported 1,3-dibromo-5,5-dimethylhydantoin (DBH) as a useful reagent for microwave-assisted aromatization of 1,3,5-trisubstituted pyrazolines under solvent-free conditions

1,3,5-Trisubstituted pyrazolines are rapidly and conveniently oxidized to their corresponding pyrazoles by 1,3-dibromo-5,5-dimethylhydantoin (DBH) under microwave irradiation and solvent-free conditions. The presence of silica gel as a supporting agent is

Synthesis of 1: H -indazoles by an electrochemical radical Csp2-H/N-H cyclization of arylhydrazones

The development of efficient and sustainable C-N bond-forming reactions to N-heterocyclic frameworks has been a long-standing interest in organic synthesis. In this work, we develop an electrochemical radical Csp2-H/N-H cyclization of arylhydrazones to 1H-indazoles. The electrochemical anodic oxidation approach was adopted to synthesize a variety of 1H-indazole derivatives in moderate to good yields. HFIP was not only employed as a solvent or the proton donor, but also can promote the formation of N free radicals. This synthetic methodology is operationally simple, and less expensive electrodes would be suitable for this chemistry. This journal is

TBHP/Cu(OAc)2 mediated oxidation of pyrazolines: A convenient method for the preparation of pyrazoles

An efficient and simple oxidative protocol has been developed for the preparation of pyrazoles from pyrazolines mediated by TBHP/Cu(OAc)2 at room temperature. The present protocol has been successfully applied for the preparation of various pyrazole compounds from heterocyclic pyrazolines.

Synthesis of zirconia doped molybdenum oxide as efficient catalysts for ultrasound assisted synthesis of substituted pyrazoles

To explore green methodology for the synthesis of mixed oxide, its catalytic activity and temperature stability of series of ZrO2/MoO3 and ZrO2 were prepared by sol-gel method and characterized by XRD, FT-IR, X-ray photoelectron spectroscopy (XPS), temperature programmed Desorption (TPD), Raman spectroscopy and transmission electron microscopes (TEM). These mixed oxides were showed high stability with nanocrystalline nature. Due to highly acidic nature of the catalysts, ultra sound assisted synthesis of substituted pyrazoles was carried out successfully with high yield. The reaction was carried out in solvent free medium, which showed green approach and energy saving reaction. Condensation of dibenzoyl methane and hydrazine to form substituted pyrazoles with 97.7% yield. The acid strength and acid amount of synthesized catalysts were determined by temperature programmed desoprtion (TPD), incorporation of zirconia into the molybdenum, network has changed its surface acid properties due to the Zr2+ and Mo6+ ions. After addition of ZrO2 on MoO3, it showed weak and strong acid sites.