2183-27-9Relevant academic research and scientific papers
Oxone?-promoted one-pot synthesis of 1-aryl-4-(organylselanyl)-1H-pyrazoles
Jacob, Raquel G.,De Oliveira, Daniela H.,Peglow, Thiago J.,Nascimento, José E. R.,Bartz, Ricardo H.
, p. 2144 - 2152 (2019)
We describe herein an efficient protocol for the one-pot synthesis of 4-organylselanylpyrazoles by direct cyclocondensation and C-H bond selenylation reactions starting from hydrazines, 1,3-diketones and diorganyl diselenides promoted by Oxone?
Microwave-assisted aromatization of 1,3,5-trisubstituted 2-pyrazolines by silica-supported N-bromosuccinimide as a useful reagent under solvent free 'dry' condition
Azarifar, Davood,Maleki, Behrooz
, p. 865 - 870 (2005)
An efficient aromatization of 1,3,5-trisubstituted 2-pyrazolines to theircorresponding pyrazoles by NBS was carried out under microwave irradiation and solvent-free conditions in moderate yields. It has also been observed that, by activating the NBS reage
N,N′,N,N′-tetrabromo-benzene-1,3-disulfonylamide as a novel reagent for oxidative aromatization of 1,3,5-trisubstituted pyrazolines under heterogeneous and solvent-free conditions
Ghorbani-Vaghei, Ramin,Azarifar, Davood,Khazaei, Ardeshir,Maleki, Behrooz
, p. 1877 - 1881 (2004)
1,3,5-Trisubstituted pyrazolines were converted to the corresponding pyrazoles in good yields under heterogeneous and solvent-free conditions by N,N′,N,N′-tetrabromo-benzene-1,3-disulfonylamide [TBBDA] at ambient temperature.
Mild oxidation of 1,3,5-trisubstituted pyrazolines with N-bromo-sulphonamides
Ghorbani-Vaghei, Ramin,Azarifar, Davood,Maleki, Behrooz
, p. 1373 - 1376 (2004)
1,3,5-Trisubstituted pyrazolines to pyrazoles are carried out efficiently in the presence of new reagents N,N,N′,N′-tetrabromo-benzene-1,3- disulfonylamine [TBBDA] and N,N′-dibromo-N,N′-1,2-ethanediylbis-(p- toluenesulphonamide) [BNBTS] in solvent-free conditions with catalytic amounts of SiO2 under microwave irradiation in high yields.
Trichloroisocyanuric acid as a novel oxidizing agent for the oxidation of 1,3,5-trisubstituted pyrazolines under both heterogeneous and solvent free conditions
Zolfigol, Mohammad Ali,Azarifar, Davood,Maleki, Behrooz
, p. 2181 - 2183 (2004)
Trichloroisocyanuric acid is used as an effective oxidizing agent for the oxidation of 1,3,5-trisubstituted pyrazolines to their corresponding pyrazoles under both heterogeneous and also solvent free conditions with good yields at room temperature.
4-(p-Chloro)phenyl-1,2,4-triazole-3,5-dione as a novel and reusable reagent for the oxidation of 1,3,5-trisubstituted pyrazolines under mild conditions
Zolfigol, Mohammad Ali,Azarifar, Davood,Mallakpour, Shadpour,Mohammadpoor-Baltork, Iraj,Forghaniha, Ali,Maleki, Behrooz,Abdollahi-Alibeik, Mohammad
, p. 833 - 836 (2006)
4-(p-Chloro)phenyl-1,3,4-triazole-3,5-dione is used as an effective oxidizing agent for the oxidation of 1,3,5-trisubstituted pyrazolines to their corresponding pyrazoles under mild conditions with moderate to good yields at room temperature.
Silica-supported 1,3-dibromo-5,5-dimethylhydantoin (DBH) as a useful reagent for microwave-assisted aromatization of 1,3,5-trisubstituted pyrazolines under solvent-free conditions
Azarifar, Davood,Zolfigol, Mohammad Ali,Maleki, Behrooz
, p. 1744 - 1746 (2004)
1,3,5-Trisubstituted pyrazolines are rapidly and conveniently oxidized to their corresponding pyrazoles by 1,3-dibromo-5,5-dimethylhydantoin (DBH) under microwave irradiation and solvent-free conditions. The presence of silica gel as a supporting agent is
Synthesis of 1: H -indazoles by an electrochemical radical Csp2-H/N-H cyclization of arylhydrazones
Alhumade, Hesham,Lei, Aiwen,Li, Dongting,Wan, Hao,Xia, Huadan,Yang, Liwen,Yi, Hong
, p. 665 - 668 (2022/01/22)
The development of efficient and sustainable C-N bond-forming reactions to N-heterocyclic frameworks has been a long-standing interest in organic synthesis. In this work, we develop an electrochemical radical Csp2-H/N-H cyclization of arylhydrazones to 1H-indazoles. The electrochemical anodic oxidation approach was adopted to synthesize a variety of 1H-indazole derivatives in moderate to good yields. HFIP was not only employed as a solvent or the proton donor, but also can promote the formation of N free radicals. This synthetic methodology is operationally simple, and less expensive electrodes would be suitable for this chemistry. This journal is
One-Pot Palladium-Catalyzed Carbonylative Sonogashira Coupling using Carbon Dioxide as Carbonyl Source
Xiong, Wenfang,Wu, Bowen,Zhu, Baiyao,Tan, Xiaobin,Wang, Lu,Wu, Wanqing,Qi, Chaorong,Jiang, Huanfeng
, p. 2843 - 2851 (2021/05/10)
Carbonylation coupling reaction has emerged as a powerful and versatile strategy for the construction of carbonyl-containing compounds in modern synthetic chemistry over the past years. Carbon dioxide, a renewable one carbon molecule, has become one of the most attractive and promising alternative carbonyl sources due to its highly abundance, nontoxicity and stability in comparison with CO in recent years. However, in most cases, a two-chamber technique was generally necessary to allow the CO-producing and CO-consuming processes to perform successfully because of the complexities and incompatibility of reaction conditions, when carbon dioxide was utilized as carbonyl source. Herein, a practical one-pot protocol using carbon dioxide as the carbonyl source for the palladium-catalyzed carbonylative Sonogashira coupling has been established, providing an expedient and practical route to a wide range of functionalized alkynones and indoxyls under mild reaction conditions. By finding a suitable catalytic system, the method allowed the CO-generating and CO-consuming processes to proceed in one pot, wherein carbon monoxide was generated in situ from the reduction of carbon dioxide in the absence of any fluoride reagents. Simple and safe operation, readily available substrates, good functional group tolerance and mild reaction conditions are the features of the method.
TBHP/Cu(OAc)2 mediated oxidation of pyrazolines: A convenient method for the preparation of pyrazoles
Kolla, Sai Teja,Somanaboina, Ramya,Bhimapaka, China Raju
, p. 1425 - 1432 (2021/02/27)
An efficient and simple oxidative protocol has been developed for the preparation of pyrazoles from pyrazolines mediated by TBHP/Cu(OAc)2 at room temperature. The present protocol has been successfully applied for the preparation of various pyrazole compounds from heterocyclic pyrazolines.
