3038-33-3

Upstream product

• 483-75-0 (-)-α-muurolene 
• 24268-39-1 γ-muurolene 
• 7647-01-0 hydrogenchloride 
• 60-29-7 diethyl ether 
• 1136-29-4 (4α,4aα,8aα)-decahydro-1,6-bis(methylene)-4-(1-methylethyl)naphthalene 
• 483-81-8 (8R,8aR)-8-Isopropyl-2,5-dimethyl-1,2,3,4,6,7,8,8a-octahydro-naphthalen-2-ol 
• 6898-04-0 1,2,3,4,5,8-Hexahydro-1-oxo-4-isopropyl-6-methoxy-naphthalin 
• 57440-63-8 C₁₆H₂₆OS₂ 
• 57440-65-0 (8R,8aR)-8-Isopropyl-5-methyl-3,4,6,7,8,8a-hexahydro-1H-naphthalen-2-one 
• 57440-64-9 (8R,8aR)-8-Isopropyl-5-methyl-1,2,3,4,6,7,8,8a-octahydro-naphthalen-2-ol 
• 77664-99-4 1-keto-4-isopropyl-1,2,3,4-tetrahydro-6-methoxynaphthalene 
• 92369-46-5 1,2,3,4,5,8-Hexahydro-1-hydroxy-4-isopropyl-6-methoxy-naphthalin 
• 81373-90-2 8-isopropyl-2-mesyloxymethyl-5-methylene-Δ²-decalene 
• 81373-88-8 2-epoxy-8-isopropyl-5-methylenedecalin 

Downstream Products

• 1080-67-7 (+)-ε-Cadinen 
• 483-73-8 cis-cadinane 
• 1136-29-4 (4α,4aα,8aα)-decahydro-1,6-bis(methylene)-4-(1-methylethyl)naphthalene 

Relevant academic research and scientific papers

A New Synthesis of (+/-)-γ2-Cadinene

8-Isopropyl-5-methylene-2-oxo-decalin (II) on nucleophilic epoxidation with dimethyloxosulphonium methylide under nitrogen atmosphere gives the epoxide (III) which undergoes stereoselective cleavage with lithium diisopropylamide to furnish the allylic alcohol, 2-hydroxymethyl-8-isopropyl-5-methyl-Δ2-decalene (IV).Conversion of IV into the corresponding mesylate (V) using mesyl chloride/TEA in dry dichloromethane and subsequent reduction of V with LAH yields (+/-)-γ2-cadinene (I).