3039-43-8

Usage

Molecular structure

Contains an isoindole-dione core with a methoxy and phenyl group attached to it.

Usage

Commonly used in organic synthesis and pharmaceutical research as a building block for the synthesis of various biologically active compounds.

Pharmacological properties

Studied for its potential antitumor and anticancer activities.

Applications

Used in the development of advanced materials and as a reagent in chemical reactions.

Potential uses

Due to its structural and functional properties, it has potential uses in various fields, including medicine, materials science, and chemical industry.

Upstream product

• 33886-50-9 4-methoxy-2-phenylisoindolin-1-one 
• 94084-62-5 5-methoxy-furan-2-carboxylic acid 
• 941-69-5 N-phenyl-maleimide 
• 103-71-9 phenyl isocyanate 
• 586-38-9 3-Methoxybenzoic acid 
• 3369-37-7 N-(o-methoxybenzylidene)aniline 

Relevant academic research and scientific papers

Ruthenium(II)-catalyzed N-substituted phthalimide synthesis via C-H activation/[3+2] annulation

Ruthenium-catalyzed intermolecular [3 + 2] annulation pathway for aromatic acids with isocyanates to afford N-substituted phthalimide in one step is demonstrated, which provides an efficient process to direct preparation of phthalimide from commercially a

A rhodium-catalyzed cascade cyclization: Direct synthesis of N-substituted phthalimides from isocyanates and benzoic acids

A rhodium(III)-catalyzed amidation between benzoic acids and isocyanates via direct functionalization of an ortho C-H bond followed by intramolecular cyclization is described. This cascade cyclization affords N-substituted phthalimides in one step in 26-91% yields. The reaction is highly atom-economical, since no theoretical waste except for water is generated in the reaction.