30392-41-7 Usage
Description
Bitolterol is a prodrug that releases colterol on activation by esterases in the lung.
Colterol is a direct-acting agonist, and the N-t-butyl group makes it β2-selective with a binding
potency equivalent to that of isoetharine and terbutaline. The ester form is lipophilic, which helps
to keep it local in the lung and resistant to COMT, which tends to increase its duration of action.
Onset begins 2 to 4 minutes after administration, and the effect can last as long as 8 hours. It
has a adverse effect profile similar to that of other β2-selective agonists, with less drowsiness
and restlessness compared to other direct-acting agonists.
Uses
β2-adrenergic receptor agonist
Definition
ChEBI: The methanesulfonate salt of bitolterol. A beta2-adrenergic receptor agonist, it is used for relief of bronchospasm in conditions such as asthma, chronic bronchitis and emphysema.
Check Digit Verification of cas no
The CAS Registry Mumber 30392-41-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,0,3,9 and 2 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 30392-41:
(7*3)+(6*0)+(5*3)+(4*9)+(3*2)+(2*4)+(1*1)=87
87 % 10 = 7
So 30392-41-7 is a valid CAS Registry Number.
InChI:InChI=1/C28H31NO5.CH4O3S/c1-18-6-10-20(11-7-18)26(31)33-24-15-14-22(23(30)17-29-28(3,4)5)16-25(24)34-27(32)21-12-8-19(2)9-13-21;1-5(2,3)4/h6-16,23,29-30H,17H2,1-5H3;1H3,(H,2,3,4)
