3040-69-5Relevant academic research and scientific papers
Supramolecular Host-Selective Activation of Iodoarenes by Encapsulated Organometallics
Bender, Trandon A.,Morimoto, Mariko,Bergman, Robert G.,Raymond, Kenneth N.,Toste, F. Dean
supporting information, p. 1701 - 1706 (2019/04/11)
Supramolecular hosts offer defined microenvironments that facilitate selective host-guest interactions, enabling reactivity that would otherwise be challenging in bulk solution. While impressive rate enhancements and selectivities have been reported, similar reactivity can often be accessed through modifications of reaction conditions even in the absence of the host. We report here an oxidative addition of aryl halides across the metal centers in Cu(I) and Pd(II) organometallics that is assisted by the presence of a supramolecular host, realized via electrostatic stabilization and increased local substrate concentrations. When reaction conditions were screened to assess background reactivity, alternative reactivity (typically decomposition) resulted, indicating that encapsulation led to host-selective reaction trajectories.
Kinetics of Alkaline Hydrolysis of Quaternary Phosphonium Salts. The Influence of Aprotic Solvents on the Hydrolysis of Ethyl(phenyl)phosphonium Iodides.
Dawber, J. Graham,Tebby, John C.,Waite, Albert A. C.
, p. 1923 - 1926 (2007/10/02)
Third-order rate constants have been determined for the hydrolyses of the ethyl(phenyl)phosphonium iodides (1) in aqueous methanol and in aqueous tetrahydrofuran.The very large increase in the rate of hydrolysis of tetra- and tri-arylphosphonium salts which is induced by the addition of tetrahydrofuran to the medium drops to almost zero for tetra- and tri-alkylphosphonium salts.This is attributed to an increase in the delocalisation of the positive charge in phosphorus, which leads to less specific solvation of the alkylphosphonium ions.
