30406-18-9

Usage

InChI:InChI=1/C7H15NO2/c1-2-3-4-5-6-7(9)8-10/h10H,2-6H2,1H3,(H,8,9)

Upstream product

• 111-71-7 heptanal 
• 599-71-3 piloty's acid 
• 2528-61-2 Heptanoic acid chloride 
• 69083-09-6 C₁₀H₁₈O₄ 
• 629-31-2 1-heptanal oxime 
• 1340546-37-3 1-heptanoyl-1,2-hydrazinedicarboxylic acid 1,2-diisopropyl ester 
• 693-39-0 1-nitroheptane 
• 104943-22-8 n-heptanoyl 2,5-dioxopyrrolidin-1-yl ester 
• 111-70-6 n-heptan1ol 
• 111-14-8 oenanthic acid 

Downstream Products

• 111-14-8 oenanthic acid 
• 7803-49-8 hydroxylamine 
• 2525-62-4 Hexyl isocyanate 

Relevant academic research and scientific papers

Visible-Light-Mediated Catalytic Hydroacylation of Dialkyl Azodicarboxylates by Graphite Flakes

A novel and efficient metal-free catalyzed hydroacylation of dialkyl azodicarboxylates is reported. Graphite flakes were found to be the most efficient catalyst among other carbon-based materials to promote this reaction. This unprecedented catalytic activity can be expanded into a wide substrate scope of aliphatic aldehydes bearing various functional groups, leading to the corresponding products in good to excellent yields.

Photoorganocatalytic One-Pot Synthesis of Hydroxamic Acids from Aldehydes

An efficient one-pot synthesis of hydroxamic acids from aldehydes and hydroxylamine is described. A fast, visible-light-mediated metal-free hydroacylation of dialkyl azodicarboxylates was used to develop the subsequent addition of hydroxylamine hydrochloride. A range of aliphatic and aromatic aldehydes were employed in this reaction to give hydroxamic acids in high to excellent yields. Application of the current methodology was demonstrated in the synthesis of the anticancer medicine vorinostat.

One-pot synthesis of hydroxamic acids from aldehydes and hydroxylamine

A one-pot oxidative transformation of aldehydes into hydroxamic acids by the use of an aqueous solution of hydroxylamine is reported. The methodology gives high yields and makes use of cheap, abundant and easily available reagents.

A two-step tandem reaction to prepare hydroxamic acids directly from alcohols

The first synthesis of hydroxamic acids from alcohols has been developed. Both benzylic and aliphatic alcohols can be tolerated and applied in this reaction. The methodology is economical, environmentally benign and high yielding. This journal is

Hypervalent iodine(III)-mediated oxidation of aldoximes to N-acetoxy or N-hydroxy amides

Treatment of various aliphatic and aromatic aldoximes with the hypervalent iodine(iii) reagents (diacetoxyiodo)benzene (DIB) or Koser's reagent [hydroxy(tosyloxy)iodo]benzene (HTIB) gave, respectively, N-acetoxy or N-hydroxy amides in good yields rather t

Angeli-Rimini's reaction on solid support: A new approach to hydroxamic acids

Angeli-Rimini's reaction has been performed for the first time on solid phase. A convenient one-step procedure for the synthesis of hydroxamic acids starting from aldehydes and solid-supported N-hydroxybenzenesulfonamide is reported. The hydroxamates are isolated in good to high yields and purities by simple evaporation of the volatile solvents, after treatment of the crude reaction mixture with sequestering agents.

A convenient method for the preparation of hydroxamic acids

A one-step conversion of carboxylic acid to hydroxamic acid, under neutral pH conditions is described. This simple, selective and efficient method was applied to a wide range of aliphatic/aromatic carboxylic acid derivatives that contain hydroxyl, halo, ester and other base sensitive groups as substituents. The method utilizes cheaply available reagents and hence it is a practical and cost effective strategy, compared to the other methods available in the literature. (C) 2000 Elsevier Science Ltd.

A FACILE PREPARATION OF ALIPHATIC HYDROXAMIC ACID FROM N,N,O-TRIS(TRIMETHYLSILYL)HYDROXYLAMINE AND ACID CHLORIDE

N,N,O-Tris(trimethylsilyl)hydroxylamine reacts readily with various aliphatic acid chlorides under mild conditions to afford the corresponding hydroxamic acids in good yields.