693-39-0Relevant articles and documents
Facile synthesis of 5-Hexyl-4-methyl-γ-butyrolactone via Nef reaction as a key step
Li, Zhi,Wang, Changwei,Feng, Pengju
, p. 795 - 799 (2015)
A racemic cis/trans mixture of 5-hexyl-4-methyl-γ-butyrolactone was easily synthesized from 1-iodoheptane in four steps with inexpensive and readily available reagents. Our new synthesis method can be potentially employed for mass production of the 4-methyl-5-hexyl-γ-butyrolactone as well as other poly-alkyl substituted γ-butyrolactones.
Crystallization Does It All: An Alternative Strategy for Stereoselective Aza-Henry Reaction
Mar?eková, Michaela,Ger?a, Peter,?oral, Michal,Moncol, Ján,Berke?, Du?an,Kolarovi?, Andrej,Jakubec, Pavol
supporting information, p. 4580 - 4584 (2019/06/17)
An efficient and experimentally straightforward method for the stereoselective synthesis of a variety of β-nitro-α-amino carboxylic acids via aza-Henry (nitro-Mannich) reaction of aldimines is disclosed, yielding either anti- or a rarely reported syn-configuration. The reaction operates directly on free glyoxylic acid and generates imine species in situ. Crystallization-controlled diastereoselectivity enables isolation of the target compounds in high enantio- and diastereomeric purities by a simple filtration.
Visible-light-promoted C-C bond cleavage: Photocatalytic generation of iminium ions and amino radicals
Cai, Shunyou,Zhao, Xinyang,Wang, Xinbo,Liu, Qisong,Li, Zigang,Wang, David Zhigang
supporting information; experimental part, p. 8050 - 8053 (2012/08/29)
Photoscissors: Structurally variable and synthetically robust iminium ions and amino radicals species could be simultaneously generated by visible-light-promoted photoredox cleavage of the C-C bonds in simple vicinal diamine precursors under very mild reaction conditions. Copyright
