3041-57-4

Upstream product

• 536-74-3 phenylacetylene 
• 106-89-8 epichlorohydrin 
• 4440-01-1 lithium phenylacetylide 

Downstream Products

• 3305-63-3 2-(3-phenyl-2-propynyl)ethylene oxide 
• 1414874-96-6 (E)-5-(iodo(phenyl)methylene)tetrahydroselenophen-3-ol 
• 1414874-72-8 1-(butylselanyl)-5-phenyl-pent-4-yn-2-yl benzoate 
• 1414874-71-7 1-butylseleno-2-hydroxy-5-phenyl-pent-4-yne 
• 566151-32-4 (+/-)-4-[(tert-butyl)dimethylsiloxy]-1-cyclohexyloxy-7-phenyl-1,6-heptadiyne 
• 566151-31-3 (+/-)-4-[(tert-butyl)dimethylsiloxy]-1-phenyl-1,6-tridecadiyne 
• 399016-61-6 1-phenyl-trideca-1,6-diyn-4-ol 
• 17733-79-8 5-phenyl-2-penten-4-yn-1-ol 

Relevant academic research and scientific papers

Boron trifluoride-tetrahydrofuran complex: A superior trigger for the Yamaguchi-Hirao alkylation of lithio-acetylides by epoxides

Use of BF3·THF complex in place of the usual BF3·OEt2 analogue in the Yamaguchi-Hirao alkylation of lithio-acetylides 2 by monosubstituted epoxides 3 gives consistently superior isolated yields (ca. 90%) of homopropargylic

Efficient and practical method for synthesizing optically active indan-2-ols by the Ti(O-i-Pr)4/2 i-PrMgCl-mediated metalative Reppe reaction

An efficient and practical synthesis of optically active indan-2-ols 1 has been developed starting from readily accessible optically active 4-siloxy-1,6-alkadiynes 2 and ethynylp-tolyl sulfone, where the metalative Reppe reaction mediated by an economical divalent titanium reagent, Ti-(O-i-Pr)4/2 i-PrMgCl, is a key step.

AN EFFICIENT METHOD FOR THE ALKYNYLATION OF OXIRANES USING ALKYNYL BORANES

Alkynyl boranes, generated in situ from lithium acetylides and boron trifluoride etherate, were found to react with oxiranes under mild reaction conditions to afford β-hydroxyacetylenes in high yields.