3305-63-3Relevant articles and documents
Efficient and practical method for synthesizing optically active indan-2-ols by the Ti(O-i-Pr)4/2 i-PrMgCl-mediated metalative Reppe reaction
Hanazawa, Takeshi,Sasaki, Kousuke,Takayama, Yuuki,Sato, Fumie
, p. 4980 - 4983 (2007/10/03)
An efficient and practical synthesis of optically active indan-2-ols 1 has been developed starting from readily accessible optically active 4-siloxy-1,6-alkadiynes 2 and ethynylp-tolyl sulfone, where the metalative Reppe reaction mediated by an economical divalent titanium reagent, Ti-(O-i-Pr)4/2 i-PrMgCl, is a key step.